Identification of residues surrounding the active site of type A botulinum neurotoxin important for substrate recognition and catalytic activity.

Identification of residues surrounding the active site of type A botulinum neurotoxin important for substrate recognition and catalytic activity.

Item
http://www.wikidata.org/entity/Q46796105
Substrate Binding Mode and Its Implication on Drug Design for Botulinum Neurotoxin AStructural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165Light chain separated from the rest of the type a botulinum neurotoxin molecule is the most catalytically active form.Structural insight into exosite binding and discovery of novel exosite inhibitors of botulinum neurotoxin serotype A through in silico screening.Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.Towards new uses of botulinum toxin as a novel therapeutic toolSystematic discovery of molecular probes targeting multiple non-orthosteric and spatially distinct sites in the botulinum neurotoxin subtype A (BoNT/A).Substrate-based inhibitors exhibiting excellent protective and therapeutic effects against Botulinum Neurotoxin A intoxicationClinical uses of botulinum neurotoxins: current indications, limitations and future developmentsThe C terminus of the catalytic domain of type A botulinum neurotoxin may facilitate product release from the active siteToxins from bacteria.Clostridial neurotoxins: mechanism of SNARE cleavage and outlook on potential substrate specificity reengineering.Tyrosine phosphorylation of botulinum neurotoxin protease domainsAugmentation of VAMP-catalytic activity of botulinum neurotoxin serotype B does not result in increased potency in physiological systems.Catalytic properties of botulinum neurotoxin subtypes A3 and A4.A novel role of C-terminus in introducing a functionally flexible structure critical for the biological activity of botulinum neurotoxin.
P2860

Identification of residues surrounding the active site of type A botulinum neurotoxin important for substrate recognition and catalytic activity.

Item
http://www.wikidata.org/entity/Q46796105
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Identification of residues sur ...... nition and catalytic activity.
@en
Identification of residues sur ...... nition and catalytic activity.
@nl
type
label
Identification of residues sur ...... nition and catalytic activity.
@en
Identification of residues sur ...... nition and catalytic activity.
@nl
prefLabel
Identification of residues sur ...... nition and catalytic activity.
@en
Identification of residues sur ...... nition and catalytic activity.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P698
P356
P1433
P1476
Identification of residues sur ...... nition and catalytic activity.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P698