Precursor-directed biosynthesis of epothilone in Escherichia coli.
about
Shotgun cloning and heterologous expression of the patellamide gene cluster as a strategy to achieving sustained metabolite production.Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.Improved precursor-directed biosynthesis in E. coli via directed evolution.Alternative sigma factor over-expression enables heterologous expression of a type II polyketide biosynthetic pathway in Escherichia coli.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products.Frontiers and opportunities in chemoenzymatic synthesis.Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?Inducible T7 RNA Polymerase-mediated Multigene Expression System, pMGX.Highly Efficient CYP167A1 (EpoK) dependent Epothilone B Formation and Production of 7-Ketone Epothilone D as a New Epothilone Derivative.Generation of novel pikromycin antibiotic products through mutasynthesis.Direct amino acid catalyzed asymmetric synthesis of polyketide sugars.Molecular variation of the nonribosomal peptide-polyketide siderophore yersiniabactin through biosynthetic and metabolic engineering.Concepts and Methods to Access Novel Antibiotics from Actinomycetes.
P2860
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P2860
Precursor-directed biosynthesis of epothilone in Escherichia coli.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@en
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@nl
type
label
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@en
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@nl
prefLabel
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@en
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@nl
P2093
P356
P1476
Precursor-directed biosynthesis of epothilone in Escherichia coli.
@en
P2093
Chaitan Khosla
Kinya Hotta
Martha Lovato Tse
R Edward Watts
P304
P356
10.1021/JA048108S
P407
P577
2004-06-01T00:00:00Z