Functional mitochondria are required for alpha-synuclein toxicity in aging yeast. - Wikidata - awgldk - TriplyDB

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

http://www.wikidata.org/entity/Q46810246

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alpha-Synuclein and neuronal cell death External and internal triggers of cell death in yeast The benefits of humanized yeast models to study Parkinson's disease Aging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicans Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast.Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease Mitochondrial lipids in neurodegeneration The migration of mitochondrial DNA fragments to the nucleus affects the chronological aging process of Saccharomyces cerevisiae The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer.Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease.Triclabendazole protects yeast and mammalian cells from oxidative stress: identification of a potential neuroprotective compound Role of alpha-synuclein protein levels in mitochondrial morphology and cell survival in cell lines.Meclizine is neuroprotective in models of Huntington's disease.Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.Autophagy proteins play cytoprotective and cytocidal roles in leucine starvation-induced cell death in Saccharomyces cerevisiae.Oxidative stress and programmed cell death in yeast.The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.Spermidine promotes mating and fertilization efficiency in model organisms.α-Synuclein and mitochondria: partners in crime?Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease.Apoptotic death of ageing yeast.Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis.Cytotoxicity of mutant huntingtin fragment in yeast can be modulated by the expression level of wild type huntingtin fragment.Yeast unfolds the road map toward alpha-synuclein-induced cell death.Apoptosis in yeast: triggers, pathways, subroutines.Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging.Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast.Contribution of yeast models to neurodegeneration research.Mitochondrion-mediated cell death: dissecting yeast apoptosis for a better understanding of neurodegeneration.Harnessing the power of yeast to unravel the molecular basis of neurodegeneration.P62/SQSTM1 at the interface of aging, autophagy, and disease.The centrality of mitochondria in the pathogenesis and treatment of Parkinson's disease.Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins.Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast Exploring the power of yeast to model aging and age-related neurodegenerative disorders.Yeast proteinopathy models: a robust tool for deciphering the basis of neurodegeneration.

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P2860

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

http://www.wikidata.org/entity/Q46810246

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

@en

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

@nl

type

label

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

@en

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

@nl

prefLabel

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

@en

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast

@en

P2093

Alessandro Bitto

http://www.w3.org/2001/XMLSchema#string

Didac Carmona-Gutierrez

http://www.w3.org/2001/XMLSchema#string

Frank Madeo

http://www.w3.org/2001/XMLSchema#string

Guido Kroemer

http://www.w3.org/2001/XMLSchema#string

Helmut Jungwirth

http://www.w3.org/2001/XMLSchema#string

Joris Winderickx

http://www.w3.org/2001/XMLSchema#string

Manuela Augsten

http://www.w3.org/2001/XMLSchema#string

Piotr Zabrocki

http://www.w3.org/2001/XMLSchema#string

Sylvia Hutter

http://www.w3.org/2001/XMLSchema#string

P2860

Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response.

An AIF orthologue regulates apoptosis in yeast.

Endonuclease G regulates budding yeast life and death.

Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae.

Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast.

A caspase-related protease regulates apoptosis in yeast.

The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis.

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7554-7560

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scholarly article

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10.1074/JBC.M708477200

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P407

P433

12

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283

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Tobias Eisenberg

Sabrina Büttner

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2008-01-11T00:00:00Z

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18192273

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