Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects. - Wikidata - awgldk - TriplyDB

Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects.

Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects.

http://www.wikidata.org/entity/Q46830854

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Plasmatic level of neurosin predicts outcome of mild cognitive impairment.Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14 Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences Kallikreins 5, 6 and 10 differentially alter pathophysiology and overall survival in an ovarian cancer xenograft model Substrate specificity of human kallikreins 1 and 6 determined by phage display.Substrate specificity determination of mouse implantation serine proteinase and human kallikrein-related peptidase 6 by phage display.The use of Fluorescence Resonance Energy Transfer (FRET) peptides for measurement of clinically important proteolytic enzymes.Functional role of kallikrein 6 in regulating immune cell survival.Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy.Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration.The multiple sclerosis degradome: enzymatic cascades in development and progression of central nervous system inflammatory disease.Differential expression of multiple kallikreins in a viral model of multiple sclerosis points to unique roles in the innate and adaptive immune response.Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors.Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).Low CSF levels of both α-synuclein and the α-synuclein cleaving enzyme neurosin in patients with synucleinopathy Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment.Characterization of Trypanosoma cruzi Sirtuins as Possible Drug Targets for Chagas Disease.Kallikrein 6 is a novel molecular trigger of reactive astrogliosis.Cathepsin K induces platelet dysfunction and affects cell signaling in breast cancer - molecularly distinct behavior of cathepsin K in breast cancer.Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis.Kallikreins - The melting pot of activity and function Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma.Progress for dengue virus diseases. Towards the NS2B-NS3pro inhibition for a therapeutic-based approach.The autolytic regulation of human kallikrein-related peptidase 6.Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines.New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family.Functional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis.Kallikrein-related peptidases: bridges between immune functions and extracellular matrix degradation.The physiology and pathobiology of human kallikrein-related peptidase 6 (KLK6).Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression.Pentapeptide sharing between Corynebacterium diphtheria toxin and the human neural protein network.Kallikrein-related peptidase-6 (KLK6) mRNA expression is an independent prognostic tissue biomarker of poor disease-free and overall survival in colorectal adenocarcinoma.Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis.Profiling the enzymatic properties and inhibition of human complement factor B.Plasma kallikrein enhances platelet aggregation response by subthreshold doses of ADP.Activation profiles and regulatory cascades of the human kallikrein-related peptidases.Transthyretin is a metallopeptidase with an inducible active site Kallikrein-related peptidase 6 orchestrates astrocyte form and function through proteinase activated receptor-dependent mechanisms

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P2860

Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects.

http://www.wikidata.org/entity/Q46830854

description

2005 nî lūn-bûn

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Substrate specificity of human ...... minoglycan activation effects.

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Substrate specificity of human ...... minoglycan activation effects.

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Substrate specificity of human ...... minoglycan activation effects.

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Substrate specificity of human ...... minoglycan activation effects.

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Substrate specificity of human ...... minoglycan activation effects.

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Journal of Biological Chemistry

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Substrate specificity of human ...... minoglycan activation effects.

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Aurelio Resende Lima

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Fabiana M Alves

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Isobel A Scarisbrick

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Luiz Juliano

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Maria Aparecida Juliano

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Michael Blaber

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Pedro Francisco Angelo

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Sachiko I Blaber

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P2860

Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4

The structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein family

Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)-antichymotrypsin

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Evaluation of the extent of the binding site in human tissue kallikrein by synthetic substrates with sequences of human kininogen fragments

Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system

Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease

Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients

Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease

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3116-3126

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10.1074/JBC.M510096200

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6

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281

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2005-12-01T00:00:00Z

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16321973

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