Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies.
about
Structure-Guided Design of a High-Affinity Platelet Integrin IIb 3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDASPlatelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesionHumanized mouse model of thrombosis is predictive of the clinical efficacy of antiplatelet agents.Exploiting the kinetic interplay between GPIbα-VWF binding interfaces to regulate hemostasis and thrombosisSimulation of platelet, thrombus and erythrocyte hydrodynamic interactions in a 3D arteriole with in vivo comparisonHumanizing thrombi in mice.Probing ADAMTS13 substrate specificity using phage displayAcalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.Humanizing mouse thrombi.Ex vivo production of platelets from stem cells.The physical spacing between the von willebrand factor d'd3- and a1- domains regulates platelet adhesion in vitro and in vivo.
P2860
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P2860
Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies.
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
Modifying murine von Willebran ...... t of human platelet therapies.
@en
Modifying murine von Willebran ...... t of human platelet therapies.
@nl
type
label
Modifying murine von Willebran ...... t of human platelet therapies.
@en
Modifying murine von Willebran ...... t of human platelet therapies.
@nl
prefLabel
Modifying murine von Willebran ...... t of human platelet therapies.
@en
Modifying murine von Willebran ...... t of human platelet therapies.
@nl
P2093
P2860
P356
P1433
P1476
Modifying murine von Willebran ...... t of human platelet therapies.
@en
P2093
Diana Tronik-Le Roux
Hairu Zhou
Hsuan-Fu Lo
Jianchun Chen
Robert C Liddington
Thomas G Diacovo
P2860
P2888
P304
P356
10.1038/NBT1373
P577
2007-12-16T00:00:00Z