Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
about
The short-lived African turquoise killifish: an emerging experimental model for ageingAssociation of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice.New therapeutic approaches for Krabbe disease: The potential of pharmacological chaperonesUsing CRISPR/Cas to study gene function and model disease in vivoPatterns of CRISPR/Cas9 activity in plants, animals and microbesGenetically engineered mouse models in oncology research and cancer medicineCo-repressor CBFA2T2 regulates pluripotency and germline developmentLoss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice.Mammalian Genotyping Using Acoustic Droplet Ejection for Enhanced Data Reproducibility, Superior Throughput, and Minimized Cross-Contamination.Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle developmentMitochondrial complex I deficiency leads to the retardation of early embryonic development in Ndufs4 knockout mice.Next-generation mammalian genetics toward organism-level systems biologyA mouse geneticist's practical guide to CRISPR applications.Precision cancer mouse models through genome editing with CRISPR-Cas9.Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJCreation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing.Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNAGeneration of an Oocyte-Specific Cas9 Transgenic Mouse for Genome Editing.CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.Recombinase-based conditional and reversible gene regulation via XTR allelesAn efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivoHematopoietic stem cells develop in the absence of endothelial cadherin 5 expressionGenetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice.Mouse genome engineering via CRISPR-Cas9 for study of immune function.An autoregulatory enhancer controls mammary-specific STAT5 functions.Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegansModel systems for studying cellular mechanisms of SCN1A-related epilepsy.Chromosome engineering in zygotes with CRISPR/Cas9.Pathway-driven discovery of epilepsy genes.Efficient generation of FVII gene knockout mice using CRISPR/Cas9 nuclease and truncated guided RNAs.Site-Directed Genome Knockout in Chicken Cell Line and Embryos Can Use CRISPR/Cas Gene Editing Technology.PrimPol prevents APOBEC/AID family mediated DNA mutagenesisRapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes.Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA RatsDetection of nucleotide-specific CRISPR/Cas9 modified alleles using multiplex ligation detection.Exclusive transmission of the embryonic stem cell-derived genome through the mouse germline.Re-visiting the Protamine-2 locus: deletion, but not haploinsufficiency, renders male mice infertile.Lineage-Specific and Non-specific Cytokine-Sensing Genes Respond Differentially to the Master Regulator STAT5.
P2860
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P2860
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@en
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@nl
type
label
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@en
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@nl
prefLabel
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@en
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@nl
P2860
P356
P1433
P1476
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.
@en
P2093
Haoyi Wang
P2860
P2888
P304
P356
10.1038/NPROT.2014.134
P577
2014-07-24T00:00:00Z