Identification of the dehydratase component of the mycobacterial mycolic acid-synthesizing fatty acid synthase-II complex.
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Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthasesThe Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residueA new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatisTHPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteriaHeterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZIdentification of a novel mycobacterial 3-hydroxyacyl-thioester dehydratase, HtdZ (Rv0130), by functional complementation in yeastPhosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesisMycobacterium tuberculosis Lsr2 is a global transcriptional regulator required for adaptation to changing oxygen levels and virulenceSynthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636.Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones.The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2Regulation of the ahpC gene encoding alkyl hydroperoxide reductase in Mycobacterium smegmatis.Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.The Non-Essential Mycolic Acid Biosynthesis Genes hadA and hadC Contribute to the Physiology and Fitness of Mycobacterium smegmatisEvolution of Mycolic Acid Biosynthesis Genes and Their Regulation during Starvation in Mycobacterium tuberculosis.Antimycobacterial Activity and Mechanism of Action of NAS-91MmpL11 protein transports mycolic acid-containing lipids to the mycobacterial cell wall and contributes to biofilm formation in Mycobacterium smegmatis.Recycling and refurbishing old antitubercular drugs: the encouraging case of inhibitors of mycolic acid biosynthesis.Mycolic acids: deciphering and targeting the Achilles' heel of the tubercle bacillusAccD6, a key carboxyltransferase essential for mycolic acid synthesis in Mycobacterium tuberculosis, is dispensable in a nonpathogenic strainDisruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability.Triclosan inhibition of mycobacterial InhA in Saccharomyces cerevisiae: yeast mitochondria as a novel platform for in vivo antimycolate assays.Unique roles of DosT and DosS in DosR regulon induction and Mycobacterium tuberculosis dormancy.MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteriaMetabolomic analysis based on 1H-nuclear magnetic resonance spectroscopy metabolic profiles in tuberculous, malignant and transudative pleural effusionPoint mutations within the fatty acid synthase type II dehydratase components HadA or HadC contribute to isoxyl resistance in Mycobacterium tuberculosisPhylogeny Trumps Chemotaxonomy: A Case Study Involving Turicella otitidis.
P2860
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P2860
Identification of the dehydratase component of the mycobacterial mycolic acid-synthesizing fatty acid synthase-II complex.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Identification of the dehydrat ...... atty acid synthase-II complex.
@en
Identification of the dehydrat ...... atty acid synthase-II complex.
@nl
type
label
Identification of the dehydrat ...... atty acid synthase-II complex.
@en
Identification of the dehydrat ...... atty acid synthase-II complex.
@nl
prefLabel
Identification of the dehydrat ...... atty acid synthase-II complex.
@en
Identification of the dehydrat ...... atty acid synthase-II complex.
@nl
P2093
P356
P1433
P1476
Identification of the dehydrat ...... atty acid synthase-II complex.
@en
P2093
Albel Singh
Alex F Evans
Alistair K Brown
Apoorva Bhatt
Elesh Saparia
P304
P356
10.1099/MIC.0.2007/012419-0
P577
2007-12-01T00:00:00Z