Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells.
about
A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescenceThe exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypesCholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptorsPrimary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulationEnhancement of renal epithelial cell functions through microfluidic-based coculture with adipose-derived stem cells.Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli.Transient receptor potential (TRP) channels: a clinical perspectiveSensing a sensor: identifying the mechanosensory function of primary ciliaIntratubular hydrodynamic forces influence tubulointerstitial fibrosis in the kidney.Glomerulocystic kidney diseaseTRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.Cilia movement regulates expression of the Raf-1 kinase inhibitor proteinDeciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron.Chronic fluid flow is an environmental modifier of renal epithelial function.Molecular pathways and therapies in autosomal-dominant polycystic kidney diseaseRegulation of blood pressure and salt homeostasis by endothelin.Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney diseaseProtein composition and movements of membrane swellings associated with primary cilia.Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors.Neuronal ciliary signaling in homeostasis and disease.Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease.Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium.A TRPM4-dependent current in murine renal primary cilia.Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.Role of renal TRP channels in physiology and pathologyTRPV4 dysfunction promotes renal cystogenesis in autosomal recessive polycystic kidney disease.Transient receptor potential channels as drug targets.OCRL1 modulates cilia length in renal epithelial cells.Polycystin-2 immunolocalization and function in zebrafishDiscrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and menCiliary dysfunction in polycystic kidney disease: an emerging model with polarizing potentialAttenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cellsPrimary cilia and kidney injury: current research status and future perspectivesPhysiology of endothelin and the kidney.Constructing and deconstructing roles for the primary cilium in tissue architecture and cancer.Calcium-mediated mechanisms of cystic expansion.Primary cilia: highly sophisticated biological sensors.The ciliary flow sensor and polycystic kidney disease.
P2860
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P2860
Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@en
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@nl
type
label
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@en
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@nl
prefLabel
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@en
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@nl
P2093
P1476
Loss of primary cilia results ...... n ARPKD collecting duct cells.
@en
P2093
Amanda L Fuson
Attila Fintha
Bradley K Yoder
Brian J Siroky
Erik M Schwiebert
Lisa M Guay-Woodford
P Darwin Bell
William B Ferguson
P304
P356
10.1152/AJPRENAL.00463.2005
P577
2006-01-05T00:00:00Z