Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors.
about
Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptorsGABAA-positive modulator selective discriminative stimulus effects of 1,1,1-trichloroethane vaporSynthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding sitePerinatal alcohol exposure leads to prolonged upregulation of hypothalamic GABA A receptors and increases behavioral sensitivity to gaboxadol.Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.Brain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits.Delta-subunit-containing GABAA-receptors mediate tonic inhibition in paracapsular cells of the mouse amygdala.Increased Motor-Impairing Effects of the Neuroactive Steroid Pregnanolone in Mice with Targeted Inactivation of the GABAA Receptor γ2 Subunit in the Cerebellum.
P2860
Q30474166-05894B91-D2EC-4659-A7FF-955187B67663Q33661170-BB1837B7-6640-421A-AC59-50F1A07F98A0Q35326774-1C387789-6C77-4436-8A10-5733D9D48D36Q35670267-731E4B2F-652A-47CC-9E03-091B109E423DQ36935606-EF747638-1DBC-4B7E-9D6D-83913BA45E99Q37080224-24EA20BD-7AB7-4CB0-A379-9FC6BC11C72AQ37320505-5C38DF40-92F6-4082-9CEF-4D58723705E1Q37382995-C57C39AB-5801-4B75-AB21-CBDB8A8BC379Q37676473-D05E18CE-DF5F-4627-8CFA-5996F1B24D19Q41586786-EE9DC0E2-0883-4E87-B9F1-046F34DA68B3
P2860
Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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name
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@en
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@nl
type
label
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@en
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@nl
prefLabel
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@en
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@nl
P2093
P2860
P50
P1476
Enhanced behavioral sensitivit ...... alpha6beta GABA(A) receptors.
@en
P2093
Hartmut Lüddens
Holger Rabe
Kati S Saarelainen
Martin Ranna
Saku T Sinkkonen
Tommi Möykkynen
P2860
P304
P356
10.1111/J.1471-4159.2007.05136.X
P407
P577
2007-11-16T00:00:00Z