6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.

6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.

Item
http://www.wikidata.org/entity/Q46933074
Endogenous repair by the activation of cell survival signalling cascades during the early stages of rat Parkinsonism.Role of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell death.Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells.The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.6-Hydroxydopamine induces mitochondrial ERK activation.Direct α-synuclein promoter transactivation by the tumor suppressor p53.Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.The SH-SY5Y cell line in Parkinson's disease research: a systematic review.Commitment of 1-methyl-4-phenylpyrinidinium ion-induced neuronal cell death by proteasome-mediated degradation of p35 cyclin-dependent kinase 5 activator.Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitroThe neurotransmitter serotonin interrupts α-synuclein amyloid maturation.Emerging roles of p53 in glial cell function in health and disease.α-synuclein and p53 functional interplay in physiopathological contexts.Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stressα-Synuclein protects neurons from apoptosis downstream of free-radical production through modulation of the MAPK signalling pathway.Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells.
P2860

6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.

Item
http://www.wikidata.org/entity/Q46933074
description
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name
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@en
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@nl
type
label
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@en
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@nl
prefLabel
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@en
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
6-Hydroxydopamine but not 1-me ...... by promoting its aggregation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921