Cell type-specific functions of the lysosomal protease cathepsin L in the heart.

Cell type-specific functions of the lysosomal protease cathepsin L in the heart.

Item
http://www.wikidata.org/entity/Q46945604
Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II.Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction.Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker.Specialized roles for cysteine cathepsins in health and disease.Formalin-Fixed, Paraffin-Embedded Tissues (FFPE) as a Robust Source for the Profiling of Native and Protease-Generated Protein Amino Termini.Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.Dual Linkage of a Locus to Left Ventricular Mass and a Cardiac Gene Co-Expression Network Driven by a Chromosome Domain.Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.Impaired turnover of autophagolysosomes in cathepsin L deficiency.Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model.Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis.Cathepsin B release from rodent intestine mucosa due to mechanical injury results in extracellular matrix damage in early post-traumatic phases.Cathepsin-L contributes to cardiac repair and remodelling post-infarction.
P2860

Cell type-specific functions of the lysosomal protease cathepsin L in the heart.

Item
http://www.wikidata.org/entity/Q46945604
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@en
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@nl
type
label
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@en
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@nl
prefLabel
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@en
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698