Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.

Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.

Item
http://www.wikidata.org/entity/Q46969030
Chassis optimization as a cornerstone for the application of synthetic biology based strategies in microbial secondary metabolismHeterologous expression of the thiopeptide antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor requires deletion of ribosomal genes from the expression construct.A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea, an Uncommon ActinomyceteStructure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides BiosynthesisCapture of micrococcin biosynthetic intermediates reveals C-terminal processing as an obligatory step for in vivo maturation.An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization.Elfamycins: inhibitors of elongation factor-Tu.YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.Challenges in the Heterologous Production of Antibiotics in Streptomyces.Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics.Radical S-Adenosylmethionine Enzymes Involved in RiPP Biosynthesis.Ribosomal Natural Products, Tailored To Fit.Reconstitution and Substrate Specificity of the Radical S-Adenosyl-methionine Thiazole C-Methyltransferase in Thiomuracin Biosynthesis.Heterologous Production of Microbial Ribosomally Synthesized and Post-translationally Modified Peptides
P2860

Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.

Item
http://www.wikidata.org/entity/Q46969030
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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2013年學術文章
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name
Capturing linear intermediates ...... ion of the thiopeptide GE2270.
@en
Capturing linear intermediates ...... ion of the thiopeptide GE2270.
@nl
type
label
Capturing linear intermediates ...... ion of the thiopeptide GE2270.
@en
Capturing linear intermediates ...... ion of the thiopeptide GE2270.
@nl
prefLabel
Capturing linear intermediates ...... ion of the thiopeptide GE2270.
@en
Capturing linear intermediates ...... ion of the thiopeptide GE2270.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Capturing linear intermediates ...... tion of the thiopeptide GE2270
@en
P2093
P304
P31
P356
10.1016/J.CHEMBIOL.2013.07.005
P433
P478
P50
P577
P5875
P698