about
Bacterial discrimination by means of a universal array approach mediated by LDR (ligase detection reaction).The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane FunctionsCatenulispora acidiphila gen. nov., sp. nov., a novel, mycelium-forming actinomycete, and proposal of Catenulisporaceae fam. nov.Actinospica robiniae gen. nov., sp. nov. and Actinospica acidiphila sp. nov.: proposal for Actinospicaceae fam. nov. and Catenulisporinae subord. nov. in the order Actinomycetales.Targets and assays for discovering novel antibacterial agents.Microbial technologies for the discovery of novel bioactive metabolites.Ribonuclease P RNA gene sequencing as a tool for molecular dereplication of myxobacterial strain collections.Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.Impact of the first Streptomyces genome sequence on the discovery and production of bioactive substances.Heterologous expression of the thiopeptide antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor requires deletion of ribosomal genes from the expression construct.Strategies for combinatorial biosynthesis with modular polyketide synthases.A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea, an Uncommon ActinomyceteMinimum Information about a Biosynthetic Gene cluster.Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024.Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis.Discovering new bioactive molecules from microbial sources.Advancing cell wall inhibitors towards clinical applications.Two Master Switch Regulators Trigger A40926 Biosynthesis in Nonomuraea sp. Strain ATCC 39727.A Derivative of the Thiopeptide GE2270A Highly Selective against Propionibacterium acnes.Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.Inorganic phosphate is a trigger factor for Microbispora sp. ATCC-PTA-5024 growth and NAI-107 production.Improved production of A40926 by Nonomuraea sp. through deletion of a pathway-specific acetyltransferase.The genus Actinoallomurus and some of its metabolites.Identification of the Entner-Doudoroff pathway in an antibiotic-producing actinomycete species.Antibacterial Paramagnetic Quinones from Actinoallomurus.Allocyclinones, hyperchlorinated angucyclinones from Actinoallomurus.Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. Part 3: Chemical derivatization.Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis.Molecular and phenotypic traits of in-vitro-selected mutants of Bifidobacterium resistant to rifaximin.Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency.Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.Antibiotic-producing ability by representatives of a newly discovered lineage of actinomycetes.A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity.Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells.Complex Regulatory Networks Governing Production of the Glycopeptide A40926.Chrolactomycins from the actinomycete actinospica.Novel Polyethers from Screening Actinoallomurus spp.Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside AntibioticsHalogenated Spirotetronates from Actinoallomurus
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P50
description
researcher
@en
wetenschapper
@nl
name
Margherita Sosio
@en
Margherita Sosio
@nl
type
label
Margherita Sosio
@en
Margherita Sosio
@nl
prefLabel
Margherita Sosio
@en
Margherita Sosio
@nl
P106
P31
P496
0000-0003-4297-6936