Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
about
Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation.Synthesis and Evaluation of α-Thymidine Analogues as Novel AntimalarialsStructure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas aeruginosa Thymidylate Kinase: From Hit to Lead GenerationPurine and pyrimidine pathways as targets in Plasmodium falciparum.Optimization of Structure Based Virtual Screening Protocols Against Thymidine Monophosphate Kinase Inhibitors as Antitubercular Agents.From crystal to compound: structure-based antimalarial drug discovery.Nucleoside analogs and tuberculosis: new weapons against an old enemy.Mechanochemical synthesis of thioureas, ureas and guanidines.Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase.Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors.Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate.Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: fragment-based QSAR and QM/MM docking studies.Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.
P2860
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P2860
Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@en
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@nl
type
label
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@en
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@nl
prefLabel
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@en
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@nl
P50
P356
P1476
Rational design of 5'-thiourea ...... hibiting mycobacterial growth.
@en
P2093
Ineke Van Daele
Matheus Froeyen
P304
P356
10.1021/JM0706158
P407
P577
2007-10-02T00:00:00Z