Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon.
about
'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP stateseIF5 has GDI activity necessary for translational control by eIF2 phosphorylationeIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core.Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2).A mechanistic overview of translation initiation in eukaryotesMolecular view of 43 S complex formation and start site selection in eukaryotic translation initiationEukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complexThe mechanism of eukaryotic translation initiation: new insights and challengesAn eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiationMolecular mechanism of scanning and start codon selection in eukaryotes.Phosphorylation of human eukaryotic initiation factor 2γ: novel site identification and targeted PKC involvement.Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivoThe C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2βCoordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complexMechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.Translation initiation factor 2gamma mutant alters start codon selection independent of Met-tRNA binding.Novel mechanisms of protein synthesis in diabetic nephropathy--role of mRNA translation.Longevity determined by developmental arrest genes in Caenorhabditis elegans.eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation.Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylationeIF5 is a dual function GAP and GDI for eukaryotic translational control.A new function and complexity for protein translation initiation factor eIF2BFail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes.Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation.Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2.Conformational selection through electrostatics: Free energy simulations of gtp and gdp binding to archaeal initiation factor 2
P2860
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P2860
Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@en
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@nl
type
label
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@en
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@nl
prefLabel
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@en
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@nl
P2860
P356
P1476
Direct binding of translation ...... actors eIF5 and eIF2B epsilon.
@en
P2093
Pankaj V Alone
P2860
P304
12636-12644
P356
10.1074/JBC.M511700200
P407
P50
P577
2006-03-07T00:00:00Z