Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
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The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymesCytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionNewborn screening for SCID identifies patients with ataxia telangiectasiaRegulation of mitochondrial functions by protein phosphorylation and dephosphorylationUbiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatmentMitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infectionNear-infrared 808 nm light boosts complex IV-dependent respiration and rescues a Parkinson-related pink1 modelBattery of behavioral tests in mice to study postoperative delirium.Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrRPlasticity of the Quinone-binding Site of the Complex II Homolog Quinol:Fumarate ReductaseStructural Insights into Ubiquinone Biosynthesis in MembranesStructure of a membrane-embedded prenyltransferase homologous to UBIAD1Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1ABCC6 localizes to the mitochondria-associated membraneEnergy failure: does it contribute to neurodegeneration?Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial healthCardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiencyAcyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity.UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development.PINK1-mediated phosphorylation of Miro inhibits synaptic growth and protects dopaminergic neurons in DrosophilaPINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease.Methods for Structural and Functional Analyses of Intramembrane Prenyltransferases in the UbiA Superfamily.Vitamin K2 biosynthetic enzyme, UBIAD1 is essential for embryonic development of miceIdentification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli.Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's diseaseVitamin k intake and plasma desphospho-uncarboxylated matrix Gla-protein levels in kidney transplant recipientsAconitase causes iron toxicity in Drosophila pink1 mutantsA novel Golgi retention signal RPWS for tumor suppressor UBIAD1.Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy.Electrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions.ISOLATION AND FUNCTIONAL ANALYSIS OF McMenA, A GENE ENCODING A 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE IN Mylabris cichorii.A high-throughput screening strategy for accurate quantification of menaquinone based on fluorescence-activated cell sorting.Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.The molecular and physiological roles of ABCC6: more than meets the eye.The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's diseaseHuman mitochondrial holocytochrome c synthase's heme binding, maturation determinants, and complex formation with cytochrome cStructure-activity relationship study of vitamin k derivatives yields highly potent neuroprotective agentsDiminished Exercise Capacity and Mitochondrial bc1 Complex Deficiency in Tafazzin-Knockdown Mice
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Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@en
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@nl
type
label
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@en
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@nl
prefLabel
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@en
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@nl
P2093
P2860
P921
P356
P1433
P1476
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
@en
P2093
Dominik M Haddad
Giovanni Esposito
Jan R Slabbaert
Janaka N Edirisinghe
Melissa Vos
Onno Schaap
R Meganathan
Stefanie Van Meensel
Sven Vilain
Vanessa A Morais
P2860
P304
P356
10.1126/SCIENCE.1218632
P407
P577
2012-05-10T00:00:00Z