The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1.
about
Disruption of G-protein γ5 subtype causes embryonic lethality in miceInhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse.Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis.Distinct functions of the laminin β LN domain and collagen IV during cardiac extracellular matrix formation and stabilization of alary muscle attachments revealed by EMS mutagenesis in Drosophila.Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration.Distinct mechanisms underlying tolerance to intermittent and constant hypoxia in Drosophila melanogaster.Competing activities of heterotrimeric G proteins in Drosophila wing maturation.Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies.Drosophila, genetic screens, and cardiac functionGalactokinase is a novel modifier of calcineurin-induced cardiomyopathy in Drosophila.An in vivo functional analysis system for renal gene discovery in Drosophila pericardial nephrocytesZebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activitySkipper genome sheds light on unique phenotypic traits and phylogenyThe orphan G protein-coupled receptor 161 is required for left-right patterningTachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in Drosophila.A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEXWnt4 is required for ostia development in the Drosophila heartGia/Mthl5 is an aorta specific GPCR required for Drosophila heart tube morphology and normal pericardial cell positioning.Genome-Wide Approaches to Drosophila Heart DevelopmentRole of the ABC transporter Mdr49 in Hedgehog signaling and germ cell migration.The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migrationHigh throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila.Drosophila models of cardiac disease.Genes and networks regulating cardiac development and function in flies: genetic and functional genomic approaches.Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation.The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.Differentiated muscles are mandatory for gas-filling of the Drosophila airway system.Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila.Retracted: Advances in the physiological and pathological implications of cholesterol.APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death.3-hydroxy-3-methylglutaryl coenzyme a reductase 1 interacts with NORK and is crucial for nodulation in Medicago truncatula.Inhibition of the 3-hydroxy-3-methyl-glutaryl-CoA reductase induces orofacial defects in zebrafish.Validating Candidate Congenital Heart Disease Genes in Drosophila.Cells on the move: Modulation of guidance cues during germ cell migration.Comprehensive functional analysis of Rab GTPases in Drosophila nephrocytes.
P2860
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P2860
The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@en
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@nl
type
label
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@en
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@nl
prefLabel
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@en
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@nl
P2093
P356
P1433
P1476
The mevalonate pathway control ...... by isoprenylation of Ggamma1.
@en
P2093
P304
P356
10.1126/SCIENCE.1127704
P407
P577
2006-07-20T00:00:00Z