about
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic nicheLysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesisThe role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancerThe role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasisMulti-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of FlightRemodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.Tissue section AFM: In situ ultrastructural imaging of native biomolecules.Lamin A/C is a risk biomarker in colorectal cancer.Correlation of Ultrasound Shear Wave Elastography with Pathological Analysis in a Xenografic Tumour ModelPre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.The pre-metastatic niche: is metastasis random?Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasisLOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis.The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.The rationale for targeting the LOX family in cancer.Lysyl oxidase in colorectal cancer.Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism.Fibrosis and Cancer: Partners in Crime or Opposing Forces?Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.Pre-metastatic niches: organ-specific homes for metastases.Meeting report: Metastasis Research Society-Chinese Tumor Metastasis Society joint conference on metastasis.AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients.Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer.The interplay between extracellular matrix remodelling and kinase signalling in cancer progression and metastasis.Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse.Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments.Charting the unexplored extracellular matrix in cancer.The extracellular matrix as a key regulator of intracellular signalling networks.Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.Removing physiological motion from intravital and clinical functional imaging dataRecent advances in understanding the complexities of metastasis
P50
Q24606366-2AA4FF21-0959-4A4D-BD2D-B58E98F66B06Q28280138-029B40EB-29C4-42AF-800F-DC34B2B1DC2CQ28304399-BC6550CA-E83F-4D13-B411-59F662B2817FQ28597660-2AE3C023-C7BE-4F5A-8ADC-F3E6DAC24966Q30364075-9D524C22-1647-41D9-81CF-091D45D7F329Q30476541-A901703D-9D77-433F-9770-74567A74670DQ30481112-16DD0248-1EC0-42E6-8372-9A90792B030DQ33361579-B9801651-1E5E-4BFE-8FFB-2BBA43B85E73Q33669055-24291536-A0E4-4BF9-8CC0-EE154702B8C9Q33688524-FF4FD03D-32EA-499A-840F-784AB1FCB0D1Q34524201-50008213-7210-4B81-953E-D7184CAA2E22Q36278233-6DE9FA43-5696-4DD3-8F63-D44F1AD8F09DQ36327483-2619A0C8-B13B-41C2-92DB-377B5BCDC4FEQ36903532-5502AE5D-AD9C-4067-B970-18E6F3AE351BQ37126990-02412968-8282-4F1C-853B-8836FCB123F6Q37346579-DB568A94-2FF2-43AC-A6E6-07200BAB733FQ37690525-0ACD3EA4-3FA0-46E6-835E-4CB5B14CEE7BQ38027412-7551423C-9E7A-4856-94EF-8B624A9273EEQ38134562-1D9086CC-E5FB-4999-8831-FA59C260054AQ38398612-E1414AFA-88F5-4E39-A810-5A8A597BF547Q38662889-2ECA2A75-3E52-4C2D-8C45-4F288FF0E4A6Q38687306-3E2FD482-4F8C-4DBA-9F13-4F234A17E3ECQ38730376-4CEDD3AC-2B0A-4BEB-A975-8D84315C5664Q38743711-DB42C821-BEE8-4DCC-9020-3D78D3151AD3Q38929128-86203DD6-F4BF-4517-ACC6-5CA5412CC090Q38939314-239E811B-3EDF-40E7-A923-A44F41513C37Q41694382-DB330220-D0F1-4A62-8FEB-A9B30578ACAFQ45987365-269B0BB9-5EDC-4162-8D0E-8C9047F7E204Q47097259-A3E8CD3A-2A5D-4171-9950-259365214412Q47134459-0A0CF6CC-3764-46EB-A38E-53973A7808C6Q47590783-C189D7A7-9589-4C66-8F2C-2DC77B39FCF2Q48247148-17007983-F5C7-4E70-B4A5-9FAE9B5BBDA3Q48371418-E2C5A057-DD7A-43EA-A376-36AA1546E2F1Q49853441-11FD36DD-5264-4B11-9247-BCAAFD2E64E9Q49990684-1AC79211-0AA3-4F34-A9D9-C6EF1F1045D5Q52315803-33F60C0F-B744-4FB0-B4D8-1BFD67CA1E05Q52365502-39DAA03E-70A0-4C7D-9F7C-FF0AB8C22D18Q54508335-A0D77A4B-4C92-4E9E-8E28-D050490A9539Q56809927-42C3B5CA-522A-4C0E-8447-9B9E165FFCC6Q58756849-22B6F057-74B8-46CC-8618-303290A17FC4
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Thomas R Cox
@ast
Thomas R Cox
@en
Thomas R Cox
@es
Thomas R Cox
@nl
Thomas R Cox
@sl
type
label
Thomas R Cox
@ast
Thomas R Cox
@en
Thomas R Cox
@es
Thomas R Cox
@nl
Thomas R Cox
@sl
prefLabel
Thomas R Cox
@ast
Thomas R Cox
@en
Thomas R Cox
@es
Thomas R Cox
@nl
Thomas R Cox
@sl
P106
P21
P31
P496
0000-0001-9294-1745