Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia.
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Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasmEpigenetic modulators as therapeutic targets in prostate cancerInactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression riskExpression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumorsMicrotubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity.The Ras-association domain family (RASSF) members and their role in human tumourigenesis.Downregulation of RUNX3 and TES by hypermethylation in glioblastoma.In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer.Hypermethylation of genes for diagnosis and risk stratification of prostate cancerPromoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasiaO6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.Promoter Methylation in Prostate Cancer and its Application for the Early Detection of Prostate Cancer Using Serum and Urine Samples.Oxidative stress and DNA methylation in prostate cancer.TGF-β mediated DNA methylation in prostate cancer.RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.Changes of protein expression in prostate cancer having lost its androgen sensitivity.Prognostic Value of Promoter Hypermethylation of Retinoic Acid Receptor Beta (RARB) and CDKN2 (p16/MTS1) in Prostate CancerEpigenetic changes in prostate cancer: implication for diagnosis and treatment.The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.Metabolic imbalance and prostate cancer progression.Association between RASSF1A promoter methylation and prostate cancer: a systematic review and meta-analysis.Measurement of GSTP1 promoter methylation in body fluids may complement PSA screening: a meta-analysisDNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoterAberrant DNA methylation and prostate cancer.Epigenetic regulation of prostate cancerTargeting epigenetic regulatory mechanisms in cancer chemoprevention.Genomic and epigenomic alterations in prostate cancer.Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling.Molecular biomarkers for cancer detection in blood and bodily fluids.Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.First results of the double-blind randomized placebo-controlled multicenter clinical trial of DIM-based therapy designed as personalized approach to reverse prostatic intraepithelial neoplasia (PIN)Precursor lesions of prostate cancer.RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking.Genome-wide methylation analysis of prostate tissues reveals global methylation patterns of prostate cancerMethylation profiles of CpG island loci in major types of human cancersProstate cancer epigenetics: a review on gene regulation.Manipulating the epigenome for the treatment of urological malignancies.DiseaseMeth version 2.0: a major expansion and update of the human disease methylation database.Promoter hypermethylation in prostate cancer.
P2860
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P2860
Aberrant CpG island hypermethylation of multiple genes in prostate cancer and prostatic intraepithelial neoplasia.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@en
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@nl
type
label
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@en
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@nl
prefLabel
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@en
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@nl
P2093
P356
P1476
Aberrant CpG island hypermethy ...... tic intraepithelial neoplasia.
@en
P2093
Hyeon Joo Lee
Kyu Sang Hwang
P304
P356
10.1002/PATH.1503
P577
2004-02-01T00:00:00Z