about
DOCK8 deficiency impairs CD8 T cell survival and function in humans and miceDOCK8 regulates signal transduction events to control immunityThe innate immune response against Brucella in humans.Asymmetric cell division during T cell development controls downstream fate.Compartmentalization in T-cell signalling: membrane microdomains and polarity orchestrate signalling and morphology.Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms.Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia.Interplay of polarity proteins and GTPases in T-lymphocyte function.The Role of the immunological Synapse Formed by Cytotoxic Lymphocytes in Immunodeficiency and Anti-Tumor immunity.Scribble acts as an oncogene in Eμ-myc-driven lymphoma.Cutting edge: DNAX accessory molecule 1-deficient CD8+ T cells display immunological synapse defects that impair antitumor immunity.DOCK8 Drives Src-Dependent NK Cell Effector Function.Impairment of intramacrophagic Brucella suis multiplication by human natural killer cells through a contact-dependent mechanism.Lethal giant larvae-1 deficiency enhances the CD8(+) effector T-cell response to antigen challenge in vivo.A method for detecting intracellular perforin in mouse lymphocytes.The Reorientation of T-Cell Polarity and Inhibition of Immunological Synapse Formation by CD46 Involves Its Recruitment to Lipid Rafts.Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity.Quantifying subcellular distribution of fluorescent fusion proteins in cells migrating within tissues.A central role for Bid in granzyme B-induced apoptosis.Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.A method for prolonged imaging of motile lymphocytes.PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF.Asymmetric T lymphocyte division in the initiation of adaptive immune responses.A 'polarized' look at alpha-tubulin cleavage by granzyme B.Tumor immune evasion arises through loss of TNF sensitivityA Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse FormationA novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapyAntagonism of IAPs Enhances CAR T-cell EfficacyVgamma9Vdelta2 T cells use a combination of mechanisms to limit the spread of the pathogenic bacteria BrucellaNatural Killer Cells Suppress T Cell-Associated Tumor Immune EvasionProtection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery
P50
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P50
description
hulumtuese
@sq
onderzoeker
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researcher
@en
հետազոտող
@hy
name
Jane Oliaro
@ast
Jane Oliaro
@en
Jane Oliaro
@es
Jane Oliaro
@nl
Jane Oliaro
@sl
type
label
Jane Oliaro
@ast
Jane Oliaro
@en
Jane Oliaro
@es
Jane Oliaro
@nl
Jane Oliaro
@sl
prefLabel
Jane Oliaro
@ast
Jane Oliaro
@en
Jane Oliaro
@es
Jane Oliaro
@nl
Jane Oliaro
@sl
P106
P21
P31
P496
0000-0002-2097-6428