Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.
about
ApoE facilitates the microglial response to amyloid plaque pathology.Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.Targeting the accomplice to thwart the culprit: a new target for the prevention of amyloid deposition.Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector.
P2860
Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.
description
2017 nî lūn-bûn
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name
Age-Dependent Effects of apoE ...... s in a Model of β-amyloidosis.
@en
Age-Dependent Effects of apoE ...... s in a Model of β-amyloidosis.
@nl
type
label
Age-Dependent Effects of apoE ...... s in a Model of β-amyloidosis.
@en
Age-Dependent Effects of apoE ...... s in a Model of β-amyloidosis.
@nl
prefLabel
Age-Dependent Effects of apoE ...... s in a Model of β-amyloidosis.
@en
Age-Dependent Effects of apoE ...... s in a Model of β-amyloidosis.
@nl
P2093
P2860
P1433
P1476
Age-Dependent Effects of apoE ...... es in a Model of β-amyloidosis
@en
P2093
Caroline M Francis
David M Holtzman
Floy R Stewart
Grace O Robinson
Hong Jiang
Jason D Ulrich
Javier Remolina Serrano
Mary Beth Finn
Patrick M Sullivan
P2860
P304
1013-1023.e4
P356
10.1016/J.NEURON.2017.11.014
P407
P577
2017-12-01T00:00:00Z