Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
about
Engineering the Delivery System for CRISPR-Based Genome Editing.Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.CRISPR-Cas-related technologies in basic and translational liver research.Chemically Modified Cpf1-CRISPR RNAs Mediate Efficient Genome Editing in Mammalian Cells.Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity.Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell Type Specific Gene Editing.CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse.Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editingRNA Therapeutics in Cardiovascular Precision MedicineAll-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivoExtension of the crRNA enhances Cpf1 gene editing in vitro and in vivoIn vivo CRISPR editing with no detectable genome-wide off-target mutations
P2860
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P2860
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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2017年學術文章
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name
Structure-guided chemical modi ...... -viral in vivo genome editing.
@en
Structure-guided chemical modi ...... -viral in vivo genome editing.
@nl
type
label
Structure-guided chemical modi ...... -viral in vivo genome editing.
@en
Structure-guided chemical modi ...... -viral in vivo genome editing.
@nl
prefLabel
Structure-guided chemical modi ...... -viral in vivo genome editing.
@en
Structure-guided chemical modi ...... -viral in vivo genome editing.
@nl
P2093
P2860
P50
P356
P1433
P1476
Structure-guided chemical modi ...... n-viral in vivo genome editing
@en
P2093
Alicia Oberholzer
Chun-Qing Song
Daniel G Anderson
Esther Mintzer
Junmei Ding
Kevin Kauffman
Luke Hyunsik Rhym
Qiongqiong Wu
Roman L Bogorad
P2860
P2888
P304
P356
10.1038/NBT.4005
P50
P577
2017-11-13T00:00:00Z