about
The BioPAX community standard for pathway data sharingSimulating microdosimetry in a virtual hepatic lobuleUsing nuclear receptor activity to stratify hepatocarcinogensUsing ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure.A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model.Systems Toxicology: Real World Applications and Opportunities.In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast projectSimulating quantitative cellular responses using asynchronous threshold Boolean network ensembles.Toxicokinetic Triage for Environmental Chemicals.Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action.Computational toxicology--a state of the science mini review.PathMiner: predicting metabolic pathways by heuristic search.Exposure science and the U.S. EPA National Center for Computational Toxicology.Systems toxicology from genes to organs.In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.Current approaches and future role of high content imaging in safety sciences and drug discovery.Predicting organ toxicity using in vitro bioactivity data and chemical structure.Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells.Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information.Development of a quantitative model of pregnane X receptor (PXR) mediated xenobiotic metabolizing enzyme induction.Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure.Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory ArchitectureUsing pathway modules as targets for assay development in xenobiotic screening.Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.The CompTox Chemistry Dashboard: a community data resource for environmental chemistry.Investigation of DUSP8 and CALCA in alcohol dependence.Virtual tissues in toxicology.In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis.Visualization based on the Enzyme Commission nomenclature.Pathway-Based Approaches for Environmental Monitoring and Risk Assessment.Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.ToxCast: Predicting Toxicity Potential Through High-Throughput Bioactivity ProfilingIncorporating Biological, Chemical, and Toxicological Knowledge Into Predictive Models of ToxicityCorrigendum: The BioPAX community standard for pathway data sharingHeurstic search for metabolic engineering: de novo synthesis of vanillinQuantitative prediction of repeat dose toxicity values using GenRA
P50
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P50
description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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name
Imran Shah
@ast
Imran Shah
@en
Imran Shah
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Imran Shah
@nl
Imran Shah
@sl
type
label
Imran Shah
@ast
Imran Shah
@en
Imran Shah
@es
Imran Shah
@nl
Imran Shah
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Imran Shah
@ast
Imran Shah
@en
Imran Shah
@es
Imran Shah
@nl
Imran Shah
@sl
P106
P1153
24071859600
P21
P31
P496
0000-0003-0808-0140