Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.
about
FOXP3 ensembles in T-cell regulationCD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.Interleukin-2 receptor signaling: at the interface between tolerance and immunityThe PD-1 pathway in tolerance and autoimmunityThe quantal theory of how the immune system discriminates between "self and non-self"Antigen-Specific Regulatory T Cells and Low Dose of IL-2 in Treatment of Type 1 DiabetesT Cells: Soldiers and Spies--The Surveillance and Control of Effector T Cells by Regulatory T CellsApplication of IL-2 therapy to target T regulatory cell functionFoxp3 protein stability is regulated by cyclin-dependent kinase 2The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cellsTGF-beta: a mobile purveyor of immune privilegeBleomycin exerts ambivalent antitumor immune effect by triggering both immunogenic cell death and proliferation of regulatory T cellsIn vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administrationHow regulatory T cells workCytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression.At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction.Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents.Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation.Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cellsDifferential effects of IL-2 and IL-21 on expansion of the CD4+ CD25+ Foxp3+ T regulatory cells with redundant roles in natural killer cell mediated antibody dependent cellular cytotoxicity in chronic lymphocytic leukemiaTh2 cell therapy of established acute graft-versus-host disease requires IL-4 and IL-10 and is abrogated by IL-2 or host-type antigen-presenting cells.GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cellsThe type of responder T-cell has a significant impact in a human in vitro suppression assay.Interleukin-2 receptor downstream events in regulatory T cells: implications for the choice of immunosuppressive drug therapyInterleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patientsSex-specific social regulation of inflammatory responses and sickness behaviors.IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells.CD4+FoxP3+ regulatory T cells from Gαi2-/- mice are functionally active in vitro, but do not prevent colitisCD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2.The role of the thymus in tolerance.FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesionsIL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells.Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.OX40 costimulation can abrogate Foxp3+ regulatory T cell-mediated suppression of antitumor immunity.Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells.Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression.Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor functionEngagement of TLR2 does not reverse the suppressor function of mouse regulatory T cells, but promotes their survivalMechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases
P2860
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P2860
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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name
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@en
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@nl
type
label
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@en
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@nl
prefLabel
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@en
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@nl
P2093
P1476
Cutting edge: IL-2 is critical ...... 5+ T cell suppressor function.
@en
P2093
Angela M Thornton
Ciriaco A Piccirillo
Erin E Donovan
Ethan M Shevach
P304
P356
10.4049/JIMMUNOL.172.11.6519
P407
P577
2004-06-01T00:00:00Z