Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene.
about
"Myc'ed messages": myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistronDifferential expression of microRNAs in different disease states.Augmentation of tumor angiogenesis by a Myc-activated microRNA clusterAngiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteinsThrombospondin-1 expression in urothelial carcinoma: prognostic significance and association with p53 alterations, tumour angiogenesis and extracellular matrix components.Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNAMyc-mediated transformation: the repression connection.Mechanisms of apoptosis by c-Myc.The v-myc oncogene.Secondary structure analysis of a minimal avian leukosis-sarcoma virus packaging signal.An Mpsi-containing heterologous RNA, but not env mRNA, is efficiently packaged into avian retroviral particles.Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.c-Myc target genes involved in cell growth, apoptosis, and metabolismp53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancersMorphine modulation of thrombospondin levels in astrocytes and its implications for neurite outgrowth and synapse formationIn vivo mechanisms by which tumors producing thrombospondin 1 bypass its inhibitory effects.An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype.Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progressionc-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis.Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation.The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood SarcomaProsaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1Thrombospondin-1 in urological cancer: pathological role, clinical significance, and therapeutic prospects.Non-cell autonomous or secretory tumor suppression.Fibroblast growth factor 8 induced downregulation of thrombospondin 1 is mediated by the MEK/ERK and PI3K pathways in breast cancer cells.Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix-loop-helix protein Id1.The Wilms' tumor gene product represses the transcription of thrombospondin 1 in response to overexpression of c-Jun.Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signalingMyb-dependent regulation of thrombospondin 2 expression. Role of mRNA stability.Methylation and silencing of the Thrombospondin-1 promoter in human cancer.Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.
P2860
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P2860
Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@en
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@nl
type
label
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@en
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@nl
prefLabel
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@en
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@nl
P2093
P2860
P356
P1476
Viral Myc oncoproteins in infe ...... ossible tumor suppressor gene.
@en
P2093
Tikhonenko AT
P2860
P304
30741-30747
P356
10.1074/JBC.271.48.30741
P407
P577
1996-11-01T00:00:00Z