OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
about
Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.β-Nicotinamide Adenine Dinucleotide (β-NAD) Inhibits ATP-Dependent IL-1β Release from Human Monocytic Cells.NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis
P2860
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
description
2018 nî lūn-bûn
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2018年の論文
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2018年学术文章
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2018年学术文章
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2018年学术文章
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2018年学术文章
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2018年学术文章
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2018年学术文章
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2018年學術文章
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2018年學術文章
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name
OLT1177, a β-sulfonyl nitrile ...... etabolic cost of inflammation.
@en
OLT1177, a β-sulfonyl nitrile ...... etabolic cost of inflammation.
@nl
type
label
OLT1177, a β-sulfonyl nitrile ...... etabolic cost of inflammation.
@en
OLT1177, a β-sulfonyl nitrile ...... etabolic cost of inflammation.
@nl
prefLabel
OLT1177, a β-sulfonyl nitrile ...... etabolic cost of inflammation.
@en
OLT1177, a β-sulfonyl nitrile ...... etabolic cost of inflammation.
@nl
P2093
P2860
P50
P356
P1476
OLT1177, a β-sulfonyl nitrile ...... metabolic cost of inflammation
@en
P2093
Angelo D'Alessandro
Carlo Marchetti
Charles A Dinarello
Charles P Neff
Curtis Henry
Curtis L Scribner
Damaris B Skouras
Gerald S Jones
Isak Tengesdal
Joseph P St Laurent
P2860
P304
E1530-E1539
P356
10.1073/PNAS.1716095115
P407
P577
2018-01-29T00:00:00Z