Connexin32-null mice develop demyelinating peripheral neuropathy.
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Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like diseaseConnexin 32 increases the proliferative response of Schwann cells to neuregulin-1 (Nrg1)Gap junctions couple astrocytes and oligodendrocytesHuman oligodendrocytes express Cx31.3: function and interactions with Cx32 mutantsConnexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning.Loss-of-function GJA12/Connexin47 mutations cause Pelizaeus-Merzbacher-like diseaseGap junctions in inherited human disorders of the central nervous system.Gap junction connexins in female reproductive organs: implications for women's reproductive healthSystemic inflammation disrupts oligodendrocyte gap junctions and induces ER stress in a model of CNS manifestations of X-linked Charcot-Marie-Tooth disease.Molecular regulators of nerve conduction - Lessons from inherited neuropathies and rodent genetic modelsGJB1/Connexin 32 whole gene deletions in patients with X-linked Charcot-Marie-Tooth disease.Expression and function of junctional adhesion molecule-C in myelinated peripheral nervesMolecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system.Connexin32 mutations cause loss of function in Schwann cells and oligodendrocytes leading to PNS and CNS myelination defectsConnexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells.Charcot-marie-tooth disease and related neuropathies: molecular basis for distinction and diagnosis.X-linked Charcot-Marie-Tooth disease and connexin32.Nodes, paranodes, and incisures: from form to function.Connexin32 in the peripheral nervous system. Functional analysis of mutations associated with X-linked Charcot-Marie-Tooth syndrome and implications for the pathophysiology of the disease.Characterization of targeted connexin32-deficient mice: a model for the human Charcot-Marie-Tooth (X-type) inherited disease.The effect of myelinating Schwann cells on axons.Connexin mutant embryonic stem cells and human diseasesThe role of gap junction channels during physiologic and pathologic conditions of the human central nervous systemGene expression in the spinal cord in female lewis rats with experimental autoimmune encephalomyelitis induced with myelin basic proteinAxonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie Tooth neuropathy.Gene expression profiling studies in regenerating nerves in a mouse model for CMT1X: uninjured Cx32-knockout peripheral nerves display expression profile of injured wild type nerves.Role of immune cells in animal models for inherited neuropathies: facts and visions.Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins.Altered tumor biology and tumorigenesis in irradiated and chemical carcinogen-treated single and combined connexin32/p27Kip1-deficient mice.A functional channel is necessary for growth suppression by Cx37.Dominantly inherited peripheral neuropathies.A novel recessive Nefl mutation causes a severe, early-onset axonal neuropathy.Connexin32-containing gap junctions in Schwann cells at the internodal zone of partial myelin compaction and in Schmidt-Lanterman incisures.Gap junction communication in myelinating gliaPathogenesis of X-linked Charcot-Marie-Tooth disease: differential effects of two mutations in connexin 32Connexinopathies: a structural and functional glimpseCharacterization of the structure and intermolecular interactions between the connexin 32 carboxyl-terminal domain and the protein partners synapse-associated protein 97 and calmodulin.Functional gap junctions in the schwann cell myelin sheath.How do mutations in GJB1 cause X-linked Charcot-Marie-Tooth disease?Axonal and periaxonal swelling precede peripheral neurodegeneration in KCC3 knockout mice.
P2860
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P2860
Connexin32-null mice develop demyelinating peripheral neuropathy.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Connexin32-null mice develop demyelinating peripheral neuropathy.
@en
Connexin32-null mice develop demyelinating peripheral neuropathy.
@nl
type
label
Connexin32-null mice develop demyelinating peripheral neuropathy.
@en
Connexin32-null mice develop demyelinating peripheral neuropathy.
@nl
prefLabel
Connexin32-null mice develop demyelinating peripheral neuropathy.
@en
Connexin32-null mice develop demyelinating peripheral neuropathy.
@nl
P2093
P2860
P1433
P1476
Connexin32-null mice develop demyelinating peripheral neuropathy.
@en
P2093
P2860
P356
10.1002/(SICI)1098-1136(199809)24:1<8::AID-GLIA2>3.0.CO;2-3
P577
1998-09-01T00:00:00Z