Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.
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Transcriptional network control of normal and leukaemic haematopoiesisHematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell CistromeMAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.Global transcriptome analyses of human and murine terminal erythroid differentiation.Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generationMiR-24 is required for hematopoietic differentiation of mouse embryonic stem cells.GATA2 deficiency.Haematopoietic and immune defects associated with GATA2 mutation.High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in miceThe LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity.GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis.An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability.Understanding transcriptional regulatory networks using computational models.An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation.A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells.The chromatin landscape and transcription factors in T cell programming.Hematopoietic transcriptional mechanisms: from locus-specific to genome-wide vantage points.The PD-1 pathway as a therapeutic target to overcome immune escape mechanisms in cancer.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.The GATA factor revolution in hematology.Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes.The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia.DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AMLGlobal transcriptome analysis for identification of interactions between coding and noncoding RNAs during human erythroid differentiation.The non-coding RNA landscape of human hematopoiesis and leukemia.Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program.Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells.Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias.GATA Factor-Dependent Positive-Feedback Circuit in Acute Myeloid Leukemia Cells.Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells.Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis.DNA methylation at enhancers identifies distinct breast cancer lineages.Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation.Distinct mechanisms of regulation of the ITGA6 and ITGB4 genes by RUNX1 in myeloid cells.Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis.
P2860
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P2860
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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@zh-hans
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name
Genome-wide analysis of transc ...... of coding and noncoding genes.
@en
Genome-wide analysis of transc ...... of coding and noncoding genes.
@nl
type
label
Genome-wide analysis of transc ...... of coding and noncoding genes.
@en
Genome-wide analysis of transc ...... of coding and noncoding genes.
@nl
prefLabel
Genome-wide analysis of transc ...... of coding and noncoding genes.
@en
Genome-wide analysis of transc ...... of coding and noncoding genes.
@nl
P2093
P50
P1433
P1476
Genome-wide analysis of transc ...... of coding and noncoding genes
@en
P2093
Dilmi Perera
Dominik Beck
John E Pimanda
Judith Schütte
Kathy Knezevic
Sarah J Kinston
Tracey A O'Brien
P304
P356
10.1182/BLOOD-2013-03-490425
P407
P577
2013-08-23T00:00:00Z