Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway.
about
Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondriaCa(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosisbeta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoformEzrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3Single vesicle analysis of endocytic fission on microtubules in vitroGlucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeletonInhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusionRole of glucocorticoids in the maturation of the rat renal Na+/H+ antiporter (NHE3)Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptorAcute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activitySodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal controlSlow intracellular accumulation of GABA(A) receptor delta subunit is modulated by brain-derived neurotrophic factorGyrating clathrin: highly dynamic clathrin structures involved in rapid receptor recyclingQuantitation of plasma membrane expression of a fusion protein of Na/H exchanger NHE3 and green fluorescence protein (GFP) in living PS120 fibroblasts.NHERF: targeting and trafficking membrane proteins.Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes.NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.Characterization of the regulation of renal Na+/H+ exchanger NHE3 by insulin.Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis.Bile formation and secretion.Luminal Na(+)/H (+) exchange in the proximal tubuleRho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting.Unique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s.NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid.NHE3 serves as a molecular tool for cAMP-mediated regulation of receptor-mediated endocytosis.Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.Phosphatidylinositol 3-kinase and the control of endosome dynamics: new players defined by structural motifs.Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3.Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.Na(+)-H(+) exchange in salivary secretory cells is controlled by an intracellular Na(+) receptor.Emerging roles of alkali cation/proton exchangers in organellar homeostasis.The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines.The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking.Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na+/H+ exchanger isoform 3 in a renal polarized epithelial cell model.Phosphatidylinositol 3-kinase and Rab5 GTPase inversely regulate the Smad anchor for receptor activation (SARA) protein independently of transforming growth factor-β1.BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction.Different ionic conditions prompt NHE2 and NHE3 translocation to the plasma membrane.Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3.
P2860
Q24293474-D9DB88C1-3C59-4C64-8276-FF82156BD7B5Q24294203-0F4F17FB-75FC-4FB4-878C-DD0374C7505DQ24556620-A67CD944-5AE4-48CB-A2C2-9D35E3470E25Q27316567-56034335-53BC-4316-BBA2-0662F8C8CA57Q27349116-D63314F5-D434-4EFB-B45C-5648071DDEFCQ28212817-0BA18AEB-D08F-4658-92AD-E9FA6B4B760EQ28219753-9D099B20-B109-4F86-8473-82D44B770D15Q28360301-AA1C031B-AA44-4C0D-965D-C2CA6718950CQ28367625-8864F2D6-9CD5-42FE-BC96-871EAC9D1BE4Q28504959-F61F9FA4-D0BE-4707-9021-3824EBB34F60Q28575397-F4852EE4-C4CB-4C41-B04F-9B7429103D3BQ28645766-AC15955C-E36D-4CB7-9830-4DB5F299543CQ30434034-B1ACD6FC-1F44-4902-8836-F13F2B7B2B2FQ30544060-181A5BA3-6A6B-4599-B59E-ECE3CD7DA2B8Q30944653-738351DE-A651-45FF-9765-F5BB49AAFE26Q31955806-DB0834A5-EF25-4B6E-87CA-8EE97E1B638EQ32031112-6F62896B-EE77-4539-8CDA-D4021F1D9AEDQ33727744-616AD9FD-0DD3-46E7-A318-427709F98B66Q33818214-584D131D-580F-4F69-86D3-7E6AC4F67DA6Q33818285-EC5D6D8E-F507-426C-B82D-9BE9655947E2Q33881922-5E5A95F0-7DD1-414D-B8EC-F938FEFCD628Q33884278-3E62330A-C441-4CCE-91F5-6BCA7555E5D6Q33922759-D34CFBCB-B4E9-4150-87D5-2CBE8DAA0D99Q34073881-89622F1D-F869-4280-A7D8-96713E0272DBQ34116039-4663DE6C-B9D6-4AAE-A515-CB3213DBBE04Q34143409-600058CE-DE42-4AA0-9725-E38C2D70182CQ34220399-08885DC3-5ABC-4C21-AA66-A29C8CD98938Q34459677-8F5E179B-E407-4A1F-9FEB-52E010841A8EQ35089685-6567150E-2D8B-4ABE-B9FB-1FD714367B8DQ35340637-36C9DCAF-1115-4718-8944-A5299C9C1DD2Q35754862-98AB3F15-E5AC-48B9-91D8-A44BAF3A22CAQ36440598-D5C22BF9-9FAF-4CFD-AD8F-36EBA4292497Q36889613-F1CE1E8F-49CB-47C1-BD12-C62708BE0C12Q37004117-837661A0-01D8-49D0-B501-3540370B77C9Q37689977-CDF623A9-5BE8-4568-A080-68378B845378Q38290476-87255FCC-FC8E-479B-861D-84C8E30CD4D2Q39286483-57E81D51-A2EA-47A7-BF55-39B675422A61Q39431004-06690920-3903-4A40-8351-262DBFFDFB73Q40170700-8EAD8596-EC00-4CD3-87B8-66A03335D1F2Q40184118-CEFE3C02-4059-4D60-9C1C-88B8410462A4
P2860
Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Endosomal recycling of the Na+ ...... idylinositol 3-kinase pathway.
@en
Endosomal recycling of the Na+ ...... idylinositol 3-kinase pathway.
@nl
type
label
Endosomal recycling of the Na+ ...... idylinositol 3-kinase pathway.
@en
Endosomal recycling of the Na+ ...... idylinositol 3-kinase pathway.
@nl
prefLabel
Endosomal recycling of the Na+ ...... idylinositol 3-kinase pathway.
@en
Endosomal recycling of the Na+ ...... idylinositol 3-kinase pathway.
@nl
P2093
P2860
P356
P1476
Endosomal recycling of the Na+ ...... tidylinositol 3-kinase pathway
@en
P2093
K Kurashima
S Grinstein
P2860
P304
20828-20836
P356
10.1074/JBC.273.33.20828
P407
P577
1998-08-01T00:00:00Z