Modelling cellular senescence as a result of telomere state.

Modelling cellular senescence as a result of telomere state.

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http://www.wikidata.org/entity/Q47734542
Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.The asymmetry of telomere replication contributes to replicative senescence heterogeneity.Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.gamma-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individualsQuantitative theory of telomere length regulation and cellular senescenceQuantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapyThe length of the shortest telomere as the major determinant of the onset of replicative senescenceSystems biology of ageing and longevity.Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.Aging and computational systems biology.Modelling the molecular mechanisms of aging.Effects of initial telomere length distribution on senescence onset and heterogeneityImmortalization of human umbilical vein endothelial cells with telomerase reverse transcriptase and simian virus 40 large T antigen.Mutual interactions between telomere heterogeneity and cell culture growth dynamics shape stochasticity of cell aging.Computing the length of the shortest telomere in the nucleus.Lymphocyte telomere dynamics and telomerase activity in inflammatory bowel disease: effect of drugs and smoking.A switch-like dynamic mechanism for the initiation of replicative senescence.
P2860

Modelling cellular senescence as a result of telomere state.

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http://www.wikidata.org/entity/Q47734542
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Modelling cellular senescence as a result of telomere state.
@en
Modelling cellular senescence as a result of telomere state.
@nl
type
label
Modelling cellular senescence as a result of telomere state.
@en
Modelling cellular senescence as a result of telomere state.
@nl
prefLabel
Modelling cellular senescence as a result of telomere state.
@en
Modelling cellular senescence as a result of telomere state.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Modelling cellular senescence as a result of telomere state.
@en
P2093
P2860
P304
P31
P356
10.1046/J.1474-9728.2003.00050.X
P433
P478
P50
P577
P5875
P698