Overexpression of F-box only protein 31 predicts poor prognosis and deregulates p38α- and JNK-mediated apoptosis in esophageal squamous cell carcinoma.

about

F-box proteins involved in cancer-associated drug resistance.

P2860

Q55253244-716CAEA2-7159-4475-BD4F-9547E89853E2

P2860

Overexpression of F-box only protein 31 predicts poor prognosis and deregulates p38α- and JNK-mediated apoptosis in esophageal squamous cell carcinoma.

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http://www.wikidata.org/entity/Q47804391

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh

2017年學術文章

@zh-hant

name

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@en

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@nl

type

Item

label

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@en

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@nl

prefLabel

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@en

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@nl

P1476

Overexpression of F-box only p ...... ageal squamous cell carcinoma.

@en

P2093

Bin Li

http://www.w3.org/2001/XMLSchema#string

Jia Liu

http://www.w3.org/2001/XMLSchema#string

Jian Gong

http://www.w3.org/2001/XMLSchema#string

Jirong Huo

http://www.w3.org/2001/XMLSchema#string

Liang Lv

http://www.w3.org/2001/XMLSchema#string

Michael S Y Huen

http://www.w3.org/2001/XMLSchema#string

Sai Wah Tsao

http://www.w3.org/2001/XMLSchema#string

Yinghuan Dai

http://www.w3.org/2001/XMLSchema#string

Yun Zhu

http://www.w3.org/2001/XMLSchema#string

Yuyong Tan

http://www.w3.org/2001/XMLSchema#string

P2860

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

The SCF ubiquitin ligase: insights into a molecular machine

Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.

Apoptosis in cancer.

F-box only protein 31 (FBXO31) negatively regulates p38 mitogen-activated protein kinase (MAPK) signaling by mediating lysine 48-linked ubiquitination and degradation of mitogen-activated protein kinase kinase 6 (MKK6)

SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication.

F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a.

FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex.

P304

145-155

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scholarly article

P356

10.1002/IJC.31040

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P433

http://www.w3.org/2001/XMLSchema#string

P478

142

http://www.w3.org/2001/XMLSchema#string

P50

A Cheung

Xin Pan

P577

2017-09-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28905993

http://www.w3.org/2001/XMLSchema#string

P921

overexpression

Overexpression of F-box only protein 31 predicts poor prognosis and deregulates p38α- and JNK-mediated apoptosis in esophageal squamous cell carcinoma.

about

P2860

P2860

Overexpression of F-box only protein 31 predicts poor prognosis and deregulates p38α- and JNK-mediated apoptosis in esophageal squamous cell carcinoma.

description

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P1433

P1476

P2093

P2860

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P433

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P50

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921