FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex.
about
F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damageTruncation of the E3 ubiquitin ligase component FBXO31 causes non-syndromic autosomal recessive intellectual disability in a Pakistani familyThe centrosomal E3 ubiquitin ligase FBXO31-SCF regulates neuronal morphogenesis and migrationDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphismA MicroRNA/Ubiquitin Ligase Feedback Loop Regulates Slug-Mediated Invasion in Breast Cancer.F-box only protein 31 (FBXO31) negatively regulates p38 mitogen-activated protein kinase (MAPK) signaling by mediating lysine 48-linked ubiquitination and degradation of mitogen-activated protein kinase kinase 6 (MKK6)SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication.F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a.Roles of F-box proteins in cancerFBXO31 promotes cell proliferation, metastasis and invasion in lung cancer.F-box protein FBXO31 directs degradation of MDM2 to facilitate p53-mediated growth arrest following genotoxic stressUbiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsMicroRNA-210 interacts with FBXO31 to regulate cancer proliferation cell cycle and migration in human breast cancerTAp63 regulates oncogenic miR-155 to mediate migration and tumour growth.CRL Ubiquitin Ligases and DNA Damage Response.Differences in hepatic gene expression as a major distinguishing factor between Korean native pig and Yorkshire.Characterization of ANKRD11 mutations in humans and mice related to KBG syndrome.Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.DEOD: uncovering dominant effects of cancer-driver genes based on a partial covariance selection method.Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.Overexpression of F-box only protein 31 predicts poor prognosis and deregulates p38α- and JNK-mediated apoptosis in esophageal squamous cell carcinoma.Degradation of FBXO31 by APC/C is regulated by AKT- and ATM-mediated phosphorylation.FBXO25 promotes cell proliferation, invasion, and migration of NSCLC.The role of F-box only protein 31 in cancer.Microcephaly, intellectual impairment, bilateral vesicoureteral reflux, distichiasis, and glomuvenous malformations associated with a 16q24.3 contiguous gene deletion and a Glomulin mutation.
P2860
Q24321698-E1675509-5AAF-4A28-8629-CA519ECD465DQ28506716-558B4CE6-69CD-4A28-B7C7-3722A930CB7BQ28584206-8D0A4AA1-4425-4C51-9092-FC0BE63D65EFQ30278581-619C87DA-FBEE-4A9D-B593-9DDBB05F8256Q33328665-E0F5108B-5B33-4BE9-BE16-1982D10A3496Q33676240-BB989ED0-8380-4CAE-9853-4DFB7A569435Q33985330-4843B0A7-B341-4E7D-AA82-B629703A9049Q34073816-92337813-82B9-40E8-94CB-E8DB811FF158Q34227637-B4C649ED-0F0A-4BB2-8A90-9F72FAA77B90Q35012352-4BF8DD39-F6DF-4928-BE7F-0C4CD0B59314Q35835275-37114747-2BF8-4B05-9DC0-B8A4D9630263Q35865629-68660141-C30A-45E6-A485-57016C3B294FQ36703456-8F6947C1-EB7B-47DE-99F5-D7B3C08EDAA6Q37213238-908E986F-1EDD-498A-9FD5-7C3089DDBE48Q37420163-AC354B5A-0D83-4B86-9260-4E5816B1023BQ38015388-1478A3E3-6E18-4372-812D-82165959DFAAQ38476349-291E506B-BE07-47F1-9497-7F327DC095F3Q38938740-1508AA3F-78B4-4963-BE22-81D929A9D143Q39460398-D55537B4-42A2-4E9D-AE4B-BB149B669192Q41145800-7CCB5ECE-DCC2-4769-A775-2A0A0C5D2EBAQ47253133-9FD83CEF-3826-4AAF-A084-9F9AB9242413Q47804391-C527AB05-EFB3-408B-8D65-F837CDABEC05Q48223689-715AA502-75D5-462A-B051-560B1497BD14Q51533176-4B44A62B-264E-4196-AE77-F289A316FD01Q52725567-10901988-93B1-4F08-AF76-DDB7BD42AC33Q53851875-D66F9EF7-EF0A-4381-9536-5A9A2FBF45A3
P2860
FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@ast
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@en
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@nl
type
label
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@ast
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@en
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@nl
prefLabel
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@ast
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@en
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@nl
P2093
P50
P1433
P1476
FBXO31 is the chromosome 16q24 ...... a component of an SCF complex.
@en
P2093
Anne-Marie Cleton-Jansen
Cees J Cornelisse
Jaclyn Lee
Jason A Powell
Joanne Crawford
Julie M Martin
Marc Lombaerts
Raman Kumar
Ross McKirdy
P304
11304-11313
P356
10.1158/0008-5472.CAN-05-0936
P407
P577
2005-12-01T00:00:00Z