Microfibril-associated glycoprotein-2 (MAGP-2) is specifically associated with fibrillin-containing microfibrils but exhibits more restricted patterns of tissue localization and developmental expression than its structural relative MAGP-1.
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The molecular genetics of Marfan syndrome and related disordersThe molecular genetics of Marfan syndrome and related microfibrillopathiesMAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrilsIdentification of a matrix-binding domain in MAGP1 and MAGP2 and intracellular localization of alternative splice formsIdentification of a major microfibril-associated glycoprotein-1-binding domain in fibrillin-2Microfibrillar proteins MAGP-1 and MAGP-2 induce Notch1 extracellular domain dissociation and receptor activationMicrofibril-associated MAGP-2 stimulates elastic fiber assemblyMicrofibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivoThe extracellular matrix protein MAGP-2 interacts with Jagged1 and induces its shedding from the cell surfaceMicrofibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.The exon structure of the human MAGP-2 gene. Similarity with the MAGP-1 gene is confined to two exons encoding a cysteine-rich region.Immunohistochemical localization of elastin, fibrillins and microfibril-associated glycoprotein-1 in the developing periodontal ligament of the rat molar.A quantitative label-free analysis of the extracellular proteome of human supraspinatus tendon reveals damage to the pericellular and elastic fibre niches in torn and aged tissueCalcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.MFAP5 loss-of-function mutations underscore the involvement of matrix alteration in the pathogenesis of familial thoracic aortic aneurysms and dissectionsMuscle fibrillin deficiency in Marfan's syndrome myopathy.Identification of the chondrocyte lineage using microfibril-associated glycoprotein-2, a novel marker that distinguishes chondrocytes from synovial cells.Microfibrillar-associated protein 5 is linked with markers of obesity-related extracellular matrix remodeling and inflammation.Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technologyMAGP2 controls Notch via interactions with RGD binding integrins: Identification of a novel ECM-integrin-Notch signaling axis.Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systemsVascular extracellular matrix and arterial mechanics.The microfibril-associated glycoproteins (MAGPs) and the microfibrillar niche.Microfibril-associated glycoprotein-1 controls human ciliary zonule development in vitro.Transcriptome analysis of endothelial cell gene expression induced by growth on matrigel matrices: identification and characterization of MAGP-2 and lumican as novel regulators of angiogenesis.MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation.Increased expression of type I collagen induced by microfibril-associated glycoprotein 2: novel mechanistic insights into the molecular basis of dermal fibrosis in scleroderma.Microfibril-associated glycoprotein-2 specifically interacts with a range of bovine and human cell types via alphaVbeta3 integrin.Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesisDistribution of the elastic fiber and associated proteins in flexor tendon reflects function.Induction of Immune Surveillance of the Dysmorphogenic Lens.Mutant fibrillin 1 from tight skin mice increases extracellular matrix incorporation of microfibril-associated glycoprotein 2 and type I collagen.Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy.Structural and compositional diversity of fibrillin microfibrils in human tissues.Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in disease.Propagation of human corneal endothelial cells: a novel dual media approach.
P2860
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P2860
Microfibril-associated glycoprotein-2 (MAGP-2) is specifically associated with fibrillin-containing microfibrils but exhibits more restricted patterns of tissue localization and developmental expression than its structural relative MAGP-1.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Microfibril-associated glycopr ...... ts structural relative MAGP-1.
@en
Microfibril-associated glycoprotein-2
@nl
type
label
Microfibril-associated glycopr ...... ts structural relative MAGP-1.
@en
Microfibril-associated glycoprotein-2
@nl
prefLabel
Microfibril-associated glycopr ...... ts structural relative MAGP-1.
@en
Microfibril-associated glycoprotein-2
@nl
P2093
P2860
P1476
Microfibril-associated glycopr ...... ts structural relative MAGP-1.
@en
P2093
E G Cleary
J S Kumaratilake
M A Gibson
M L Finnis
P2860
P304
P356
10.1177/002215549804600802
P577
1998-08-01T00:00:00Z