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Is cardiac magnetic resonance imaging causing DNA damage?Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assayThe vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachmentMammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantroneFormation of nuclear stress granules involves HSF2 and coincides with the nucleolar localization of Hsp70Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosisThe highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeresMultiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin.Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpointExpression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice.Loss of p38gamma MAPK induces pleiotropic mitotic defects and massive cell death.Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.Integrin trafficking regulated by Rab21 is necessary for cytokinesis.Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stressNovel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.Inhibition of Aurora kinases perturbs chromosome alignment and spindle checkpoint signaling in rat spermatocytes.High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint.Effects of the DNA topoisomerase II inhibitor merbarone in male mouse meiotic divisions in vivo: cell cycle arrest and induction of aneuploidy
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description
hulumtues
@sq
onderzoeker
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researcher
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հետազոտող
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name
Marko J. Kallio
@ast
Marko J. Kallio
@en
Marko J. Kallio
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Marko J. Kallio
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Marko J. Kallio
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type
label
Marko J. Kallio
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Marko J. Kallio
@en
Marko J. Kallio
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Marko J. Kallio
@nl
Marko J. Kallio
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prefLabel
Marko J. Kallio
@ast
Marko J. Kallio
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Marko J. Kallio
@es
Marko J. Kallio
@nl
Marko J. Kallio
@sl
P106
P1153
7006280880
P21
P31
P496
0000-0002-6345-1680