Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
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Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathyTrafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segmentDendritic spikes amplify the synaptic signal to enhance detection of motion in a simulation of the direction-selective ganglion cellStructural Basis for the Modulation of the Neuronal Voltage-Gated Sodium Channel NaV1.6 by CalmodulinNeurobiology: a channel sets the gain on painEvidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis.Inhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry.Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons.Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice.rAAV-mediated subcellular targeting of optogenetic tools in retinal ganglion cells in vivoFunctional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth.Organization and maintenance of molecular domains in myelinated axonsMolecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunitsDysfunction of the Scn8a voltage-gated sodium channel alters sleep architecture, reduces diurnal corticosterone levels, and enhances spatial memory.Exaggerated emotional behavior in mice heterozygous null for the sodium channel Scn8a (Nav1.6).Undersized dendritic arborizations in retinal ganglion cells of the rd1 mutant mouse: a paradigm of early onset photoreceptor degenerationReduced Retinal Function in the Absence of Na(v)1.6.Localization of the paranodal protein Caspr in the mammalian retina.Sodium channel SCN8A (Nav1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability.Functional properties and differential neuromodulation of Na(v)1.6 channels.Different mechanisms generate maintained activity in ON and OFF retinal ganglion cells.Na Channel β Subunits: Overachievers of the Ion Channel Family.Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expressionRole of calcium and calpain in the downregulation of voltage-gated sodium channel expression by the pyrethroid pesticide deltamethrinRbfox proteins regulate alternative splicing of neuronal sodium channel SCN8ASubunit dependence of Na channel slow inactivation and open channel block in cerebellar neuronsTargeted Expression of Channelrhodopsin-2 to the Axon Initial Segment Alters the Temporal Firing Properties of Retinal Ganglion Cells.Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal developmentFrequency Responses of Rat Retinal Ganglion Cells.Elevated Neuronal Excitability Due to Modulation of the Voltage-Gated Sodium Channel Nav1.6 by Aβ1-42.Action potential initiation and propagation: upstream influences on neurotransmissionSingle amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder.FGF14 localization and organization of the axon initial segmentMolecular components underlying nongenomic thyroid hormone signaling in embryonic zebrafish neurons.Scn8a voltage-gated sodium channel mutation alters seizure and anxiety responses to acute stress.The axon initial segment in nervous system disease and injuryHomeostatic signaling and the stabilization of neural function.Prosthetic vision: devices, patient outcomes and retinal research.A hierarchy of cell intrinsic and target-derived homeostatic signaling.Near-Perfect Synaptic Integration by Nav1.7 in Hypothalamic Neurons Regulates Body Weight.
P2860
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P2860
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
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2006年學術文章
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2006年學術文章
@zh-hant
name
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
@en
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
@nl
type
label
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
@en
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
@nl
prefLabel
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
@en
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels.
@nl
P1476
Impaired firing and cell-specific compensation in neurons lacking nav1.6 sodium channels
@en
P2093
Gary Matthews
P304
P356
10.1523/JNEUROSCI.1101-06.2006
P407
P577
2006-07-01T00:00:00Z