Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y. - Wikidata - awgldk - TriplyDB

Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y.

Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y.

http://www.wikidata.org/entity/Q47881235

about

CHK2 kinase expression is down-regulated due to promoter methylation in non-small cell lung cancer The transcription factor p53: not a repressor, solely an activator Irofulven induces replication-dependent CHK2 activation related to p53 status Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63.Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.Bayesian Weibull tree models for survival analysis of clinico-genomic data NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue.Transcription factors involved in prostate gland adaptation to androgen deprivation.p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.p53 suppresses the Nrf2-dependent transcription of antioxidant response genes.Expression of p53 target genes in the early phase of long-term potentiation in the rat hippocampal CA1 area The Role of Wild-Type p53 in Cisplatin-Induced Chk2 Phosphorylation and the Inhibition of Platinum Resistance with a Chk2 Inhibitor Phytoestrogen Bakuchiol Exhibits In Vitro and In Vivo Anti-breast Cancer Effects by Inducing S Phase Arrest and Apoptosis The dark side of a tumor suppressor: anti-apoptotic p53.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.ATM-dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability.Hsp90 induces increased genomic instability toward DNA-damaging agents by tuning down RAD53 transcription.Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe.Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines.14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2.

P2860

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P2860

Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y.

http://www.wikidata.org/entity/Q47881235

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

@zh-my

2004年学术文章

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2004年學術文章

@yue

2004年學術文章

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name

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

@en

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

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type

label

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

@en

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

@nl

prefLabel

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

@en

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Negative regulation of Chk2 ex ...... ing transcription factor NF-Y.

@en

P2093

Fumitaka Fujita

http://www.w3.org/2001/XMLSchema#string

Hiroshi Murakami

http://www.w3.org/2001/XMLSchema#string

Hiroyuki Niida

http://www.w3.org/2001/XMLSchema#string

Makoto Itoh

http://www.w3.org/2001/XMLSchema#string

Makoto Nakanishi

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Taido Matsui

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Takashi Joh

http://www.w3.org/2001/XMLSchema#string

Tomoharu Inoue

http://www.w3.org/2001/XMLSchema#string

Yuko Katsuno

http://www.w3.org/2001/XMLSchema#string

P2860

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

PUMA, a novel proapoptotic gene, is induced by p53

Wild-type p53 binds to the TATA-binding protein and represses transcription

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y

SUMO-1 modification activates the transcriptional response of p53

P304

25093-25100

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P31

scholarly article

P356

10.1074/JBC.M403232200

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P407

P433

24

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P478

279

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P577

2004-03-25T00:00:00Z

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P698

15044452

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