Conformational changes modulate the activity of human RAD51 protein.
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Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA moleculesHuman Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function.Conservation of a conformational switch in RadA recombinase fromMethanococcus maripaludisRAD51 Protein ATP Cap Regulates Nucleoprotein Filament StabilityRad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics.Real-time assembly and disassembly of human RAD51 filaments on individual DNA moleculesSubunit interface residues F129 and H294 of human RAD51 are essential for recombinase function.A chemical compound that stimulates the human homologous recombination protein RAD51Human Rad51 mediated DNA unwinding is facilitated by conditions that favour Rad51-dsDNA aggregationDesign of potent inhibitors of human RAD51 recombinase based on BRC motifs of BRCA2 protein: modeling and experimental validation of a chimera peptide.Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution.Visualizing RAD51-mediated joint molecules: implications for recombination mechanism and the effect of sequence heterology.HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filamentThe RecA/RAD51 protein drives migration of Holliday junctions via polymerization on DNA.Homologous recombination conserves DNA sequence integrity throughout the cell cycle in embryonic stem cellsRAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.Human DNA helicase B functions in cellular homologous recombination and stimulates Rad51-mediated 5'-3' heteroduplex extension in vitro.Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity.Real-time measurements of the nucleation, growth and dissociation of single Rad51-DNA nucleoprotein filamentsInter-subunit interactions that coordinate Rad51's activities.ATP-dependent nucleosome unwrapping catalyzed by human RAD51The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchangeFrom meiosis to postmeiotic events: uncovering the molecular roles of the meiosis-specific recombinase Dmc1.pH-dependent activities and structural stability of loop-2-anchoring helix of RadA recombinase from Methanococcus voltae.A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange.Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence.Potassium chloride and rare earth elements improve plant growth and increase the frequency of the Agrobacterium tumefaciens-mediated plant transformation.Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA.
P2860
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P2860
Conformational changes modulate the activity of human RAD51 protein.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Conformational changes modulate the activity of human RAD51 protein.
@en
Conformational changes modulate the activity of human RAD51 protein.
@nl
type
label
Conformational changes modulate the activity of human RAD51 protein.
@en
Conformational changes modulate the activity of human RAD51 protein.
@nl
prefLabel
Conformational changes modulate the activity of human RAD51 protein.
@en
Conformational changes modulate the activity of human RAD51 protein.
@nl
P2093
P1476
Conformational changes modulate the activity of human RAD51 protein.
@en
P2093
Alicja Z Stasiak
Andrzej Stasiak
Jean-Yves Masson
P304
P356
10.1016/J.JMB.2004.02.022
P407
P577
2004-04-01T00:00:00Z