Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules - Wikidata - awgldk - TriplyDB

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

http://www.wikidata.org/entity/Q24654281

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Purified human BRCA2 stimulates RAD51-mediated recombination The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51 Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optically trapped nanoprobe.Crystal structure of the phage T4 recombinase UvsX and its functional interaction with the T4 SF2 helicase UvsW RAD51 Protein ATP Cap Regulates Nucleoprotein Filament Stability High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination Watching individual proteins acting on single molecules of DNA.Direct observation of twisting steps during Rad51 polymerization on DNA.Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques.Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA Cooperative conformational transitions keep RecA filament active during ATPase cycle Single molecule techniques in DNA repair: a primer Subunit interface residues F129 and H294 of human RAD51 are essential for recombinase function.Imaging the DNA damage response with PET and SPECT Visualizing protein-DNA interactions at the single-molecule level Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.Single-molecule imaging brings Rad51 nucleoprotein filaments into focus.Combining optical trapping, fluorescence microscopy and micro-fluidics for single molecule studies of DNA-protein interactions.Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution.Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor Visualizing RAD51-mediated joint molecules: implications for recombination mechanism and the effect of sequence heterology.Future challenges in single-molecule fluorescence and laser trap approaches to studies of molecular motors.BRCA2: Shining light on the regulation of DNA-binding selectivity by RAD51.Reconstitution of recombination-associated DNA synthesis with human proteins.Exploring protein-DNA interactions in 3D using in situ construction, manipulation and visualization of individual DNA dumbbells with optical traps, microfluidics and fluorescence microscopy.Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins Real-time observation of strand exchange reaction with high spatiotemporal resolution Functions of the Snf2/Swi2 family Rad54 motor protein in homologous recombination.RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.Investigating Deinococcus radiodurans RecA protein filament formation on double-stranded DNA by a real-time single-molecule approach.Rad51 paralogues Rad55-Rad57 balance the antirecombinase Srs2 in Rad51 filament formation.Ca2+ improves organization of single-stranded DNA bases in human Rad51 filament, explaining stimulatory effect on gene recombination.Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament.Architectural plasticity of human BRCA2-RAD51 complexes in DNA break repair.Probing Rad51-DNA interactions by changing DNA twist.The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination.Single-molecule views of protein movement on single-stranded DNA.

P2860

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P2860

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

http://www.wikidata.org/entity/Q24654281

description

2009 nî lūn-bûn

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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@ast

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@en

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@nl

type

label

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@ast

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@en

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@nl

prefLabel

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@ast

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@en

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

@en

P2093

Ichiro Amitani

http://www.w3.org/2001/XMLSchema#string

Jovencio Hilario

http://www.w3.org/2001/XMLSchema#string

Ronald J Baskin

http://www.w3.org/2001/XMLSchema#string

Stephen C Kowalczykowski

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P2860

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

RecBCD enzyme switches lead motor subunits in response to chi recognition

Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function.

A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase

Molecular views of recombination proteins and their control

Rad54 protein promotes branch migration of Holliday junctions

Mechanism of homologous recombination: mediators and helicases take on regulatory functions

Microtubule polymerization dynamics

Mechanical processes in biochemistry

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