Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
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A family of AP-2 proteins down-regulate manganese superoxide dismutase expressionTranscription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cellsA subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humansActivator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cellsTFAP2A mutations result in branchio-oculo-facial syndromeAP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cellsProof of concept for microarray-based detection of DNA-binding oncogenes in cell extractsIdentification of novel cholesteatoma-related gene expression signatures using full-genome microarraysCloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation propertiesAnalysis of the domain requirement in Gas1 growth suppressing activityVascular channels formed by subpopulations of PECAM1+ melanoma cells.CREB inhibits AP-2alpha expression to regulate the malignant phenotype of melanoma.n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2alpha and telomerase activity.Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells.Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo.MUC18 Differentially Regulates Pro-Inflammatory and Anti-Viral Responses in Human Airway Epithelial Cells.Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells.Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherenceExpression of transcription factor AP-2 in colorectal adenomas and adenocarcinomas; comparison of immunohistochemistry and in situ hybridisation.Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells.The emerging role of the thrombin receptor (PAR-1) in melanoma metastasis--a possible therapeutic target.CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18.MUC18 Regulates Lung Rhinovirus Infection and Inflammation.TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF.Bioimmunotherapy for melanoma using fully human antibodies targeting MCAM/MUC18 and IL-8.Expression of transcription factor AP-2alpha predicts survival in epithelial ovarian cancerAP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development.Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review.Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment.Driving transcriptional regulators in melanoma metastasis.Immune alterations in malignant melanoma and current immunotherapy concepts.Melanoma biomolecules: independently identified but functionally intertwined.Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail.Identification of the elements regulating the expression of the cell adhesion molecule MCAM/MUC18. Loss of AP-2 is not required for MCAM expression in melanoma cell lines.The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasisEctopic expression of AP-2α transcription factor suppresses glioma progression.miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy.AP2 suppresses osteoblast differentiation and mineralization through down-regulation of Frizzled-1.The HLJ1-targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer.
P2860
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P2860
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@en
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@nl
type
label
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@en
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@nl
prefLabel
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@en
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@nl
P2093
P2860
P356
P1476
Loss of AP-2 results in up-reg ...... tasis of human melanoma cells.
@en
P2093
Gershenwald JE
Tainsky MA
P2860
P304
16501-16508
P356
10.1074/JBC.273.26.16501
P407
P577
1998-06-01T00:00:00Z