Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.
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The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiencyIdentification of novel VHL target genes and relationship to hypoxic response pathwaysExome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaState of the science: an update on renal cell carcinomaGenetic and Chromosomal Aberrations and Their Clinical Significance in Renal NeoplasmsRole of DNA methylation in renal cell carcinomaAdverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research networkTumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancersChromosome 3p allele loss in early invasive breast cancer: detailed mapping and association with clinicopathological features.Management of Gene Variants of Unknown Significance: Analysis Method and Risk Assessment of the VHL Mutation p.P81S (c.241C>T)Novel tumor suppressor locus in human chromosome region 3p14.2.Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors.Arteriovenous malformation and thyroid metastasis from underlying renal cell carcinoma, an unusual presentation of malignancy: A case report.Role of chromosome 3p12-p21 tumour suppressor genes in clear cell renal cell carcinoma: analysis of VHL dependent and VHL independent pathways of tumorigenesis.A Comprehensive Study of Progressive Cytogenetic Alterations in Clear Cell Renal Cell Carcinoma and a New Model for ccRCC Tumorigenesis and ProgressionAn analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: evidence for modifier effects.Metastatic clear cell carcinoma of the kidney: therapeutic role of bevacizumabAlterations of the WNT7A gene in clear cell renal cell carcinomasVHL, the story of a tumour suppressor gene.Methylation of the RASSF1A gene in human cancers.Use of the spontaneous Tsc2 knockout (Eker) rat model of hereditary renal cell carcinoma for the study of renal carcinogens.HIF hydroxylation and the mammalian oxygen-sensing pathwayNovel therapies for renal cell carcinoma--an update.Renal cell carcinoma and the use of sorafenib.Familial clear cell renal cell carcinoma (FCRC): clinical features and mutation analysis of the VHL, MET, and CUL2 candidate genes.Reconsideration of biallelic inactivation of the VHL tumour suppressor gene in hemangioblastomas of the central nervous system.miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma.DNA Methylation and Flavonoids in Genitourinary Cancers.CDKNA2A mutation analysis, protein expression, and deletion mapping of chromosome 9p in conventional clear-cell renal carcinomas: evidence for a second tumor suppressor gene proximal to CDKN2A.Current status of targeted therapy for advanced renal cell carcinomaGenome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma.Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells.Molecularly targeted therapy in renal cell carcinoma.High-grade clear cell renal cell carcinoma has a higher angiogenic activity than low-grade renal cell carcinoma based on histomorphological quantification and qRT-PCR mRNA expression profileDNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas.Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas.SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinomaInvestigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma.Loss of heterozygosity and copy number abnormality in clear cell renal cell carcinoma discovered by high-density affymetrix 10K single nucleotide polymorphism mapping array.
P2860
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P2860
Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Inactivation of the von Hippel ...... ear cell renal tumourigenesis.
@en
Inactivation of the von Hippel-Lindau
@nl
type
label
Inactivation of the von Hippel ...... ear cell renal tumourigenesis.
@en
Inactivation of the von Hippel-Lindau
@nl
prefLabel
Inactivation of the von Hippel ...... ear cell renal tumourigenesis.
@en
Inactivation of the von Hippel-Lindau
@nl
P2093
P2860
P1476
Inactivation of the von Hippel ...... ear cell renal tumourigenesis.
@en
P2093
A H Prowse
N A Affara
S C Clifford
P2860
P304
P356
10.1002/(SICI)1098-2264(199807)22:3<200::AID-GCC5>3.0.CO;2-#
P577
1998-07-01T00:00:00Z