Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer.
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Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancerZinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repairSOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epitheliumA new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen geneThe new collagen gene COL27A1 contains SOX9-responsive enhancer elementsBeta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healingThe transcription factor CCAAT-binding factor CBF/NF-Y regulates the proximal promoter activity in the human alpha 1(XI) collagen gene (COL11A1)Compound effects of point mutations causing campomelic dysplasia/autosomal sex reversal upon SOX9 structure, nuclear transport, DNA binding, and transcriptional activationCOL11A2 collagen gene transcription is differentially regulated by EWS/ERG sarcoma fusion protein and wild-type ERGRegulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9A Krüppel-associated box-zinc finger protein, NT2, represses cell-type-specific promoter activity of the alpha 2(XI) collagen geneMint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1The transcription factor Lc-Maf participates in Col27a1 regulation during chondrocyte maturationArid5a cooperates with Sox9 to stimulate chondrocyte-specific transcriptionThe chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bonesCREB-AP1 protein complexes regulate transcription of the collagen XXIV gene (Col24a1) in osteoblastsThe transcription factor SOX9 regulates cell cycle and differentiation genes in chondrocytic CFK2 cellsIdentification of an enhancer sequence within the first intron required for cartilage-specific transcription of the alpha2(XI) collagen geneFGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glandsThe transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6SRY-related HMG box 9 regulates the expression of Col4a2 through transactivating its enhancer element in mesangial cellsPotential role of Sox9 in patterning tracheal cartilage ring formation in an embryonic mouse model.Specific amelogenin gene splice products have signaling effects on cells in culture and in implants in vivo.Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9.Identification of SOX9 interaction sites in the genome of chondrocytesInteractions between Sox9 and beta-catenin control chondrocyte differentiation.Fine mapping of chromosome 17 translocation breakpoints > or = 900 Kb upstream of SOX9 in acampomelic campomelic dysplasia and a mild, familial skeletal dysplasiaOsteo-chondroprogenitor cells are derived from Sox9 expressing precursors.Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytesSOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte.Chondrodysplasias due to proteoglycan defects.Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements.Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathwayAnti-DKK1 antibody promotes bone fracture healing through activation of β-catenin signaling.Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytesInfluence of 1α, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes.L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activityRegulation of the human SOX9 promoter by Sp1 and CREBSOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
P2860
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P2860
Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@en
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@nl
type
label
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@en
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@nl
prefLabel
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@en
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@nl
P2860
P356
P1476
Chondrocyte-specific enhancer ...... l2a1 tissue-specific enhancer.
@en
P2093
Lefebvre V
de Crombrugghe B
P2860
P304
14998-15006
P356
10.1074/JBC.273.24.14998
P407
P577
1998-06-01T00:00:00Z