Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.
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Functional analysis of the leading malaria vaccine candidate AMA-1 reveals an essential role for the cytoplasmic domain in the invasion processStructure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory AntibodyNovel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytesMolecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptideProduction, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic VariationBinding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion.Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoitesProtection of rhesus monkeys by a DNA prime/poxvirus boost malaria vaccine depends on optimal DNA priming and inclusion of blood stage antigens.An inhibitory antibody blocks interactions between components of the malarial invasion machinery.Extreme polymorphism in a vaccine antigen and risk of clinical malaria: implications for vaccine development.Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasionInteraction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites.Distinct patterns of diversity, population structure and evolution in the AMA1 genes of sympatric Plasmodium falciparum and Plasmodium vivax populations of Papua New Guinea from an area of similarly high transmissionJuxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodiesIdentification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 proteinUse of immunodampening to overcome diversity in the malarial vaccine candidate apical membrane antigen 1.Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.The Plasmodium vivax rhoptry neck protein 5 is expressed in the apical pole of Plasmodium vivax VCG-1 strain schizonts and binds to human reticulocytes.Comparative analysis of the profiles of IgG subclass-specific responses to Plasmodium falciparum apical membrane antigen-1 and merozoite surface protein-1 in naturally exposed individuals living in malaria hypoendemic settings, Iran.The effect of daily co-trimoxazole prophylaxis on natural development of antibody-mediated immunity against P. falciparum malaria infection in HIV-exposed uninfected Malawian childrenCrystal structure of Plasmodium knowlesi apical membrane antigen 1 and its complex with an invasion-inhibitory monoclonal antibody.Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide DisplayPlasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development.Structural basis of antigenic escape of a malaria vaccine candidateThe moving junction, a key portal to host cell invasion by apicomplexan parasites.Evaluation of the immunogenicity and vaccine potential of recombinant Plasmodium falciparum merozoite surface protein 8.Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth CohortHeterologous expression of plasmodial proteins for structural studies and functional annotation.Genetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming 'vaccine resistant malaria'.Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.World Malaria Day 2009: what malaria knows about the immune system that immunologists still do not.Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1.Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication.Alanine mutagenesis of the primary antigenic escape residue cluster, c1, of apical membrane antigen 1.Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.Plasmodium vivax ligand-receptor interaction: PvAMA-1 domain I contains the minimal regions for specific interaction with CD71+ reticulocytes.Prediction of merozoite surface protein 1 and apical membrane antigen 1 vaccine efficacies against Plasmodium chabaudi malaria based on prechallenge antibody responses.PvRON2, a new Plasmodium vivax rhoptry neck antigen.Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.
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P2860
Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@en
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@nl
type
label
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@en
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@nl
prefLabel
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@en
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@nl
P2093
P2860
P356
P1476
Fine mapping of an epitope rec ...... ate apical membrane antigen 1.
@en
P2093
Adrian H Batchelor
Alan W Thomas
Chrislaine Withers-Martinez
Christine R Collins
Graham A Bentley
Michael J Blackman
P2860
P304
P356
10.1074/JBC.M610562200
P407
P577
2006-12-27T00:00:00Z