Involvement of flap endonuclease 1 in base excision DNA repair. - Wikidata - awgldk - TriplyDB

Involvement of flap endonuclease 1 in base excision DNA repair.

Involvement of flap endonuclease 1 in base excision DNA repair.

http://www.wikidata.org/entity/Q48038198

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Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determination WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork Domain specific interaction in the XRCC1-DNA polymerase beta complex Expression profile of genes regulated by activity of the Na-H exchanger NHE1 The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease Human AP endonuclease 1: a potential marker for the prediction of environmental carcinogenesis risk Molecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshii Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2 Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway Accessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts.Expression and biochemical characterization of the Plasmodium falciparum DNA repair enzyme, flap endonuclease-1 (PfFEN-1)Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1 Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells.Mechanism underlying replication protein a stimulation of DNA ligase I.Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair.Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism.Base excision repair of tandem modifications in a methylated CpG dinucleotide.FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells.Human RECQL5beta stimulates flap endonuclease 1 Nuclear DNA polymerase beta from Leishmania infantum. Cloning, molecular analysis and developmental regulation.A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathways.Eukaryotic DNA polymerases: proposal for a revised nomenclature.Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major.Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer.The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.

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Involvement of flap endonuclease 1 in base excision DNA repair.

http://www.wikidata.org/entity/Q48038198

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

@zh-my

1998年学术文章

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1998年學術文章

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1998年學術文章

@zh-hant

name

Involvement of flap endonuclease 1 in base excision DNA repair.

@en

Involvement of flap endonuclease 1 in base excision DNA repair.

@nl

type

label

Involvement of flap endonuclease 1 in base excision DNA repair.

@en

Involvement of flap endonuclease 1 in base excision DNA repair.

@nl

prefLabel

Involvement of flap endonuclease 1 in base excision DNA repair.

@en

Involvement of flap endonuclease 1 in base excision DNA repair.

@nl

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JBC.273.15.8842

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Journal of Biological Chemistry

P1476

Involvement of flap endonuclease 1 in base excision DNA repair

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K Kim

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S Biade

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P2860

Instability and decay of the primary structure of DNA

Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

Essential amino acids for substrate binding and catalysis of human flap endonuclease 1

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

Xenopus Y-box transcription factors: molecular cloning, functional analysis and developmental regulation

p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

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8842-8848

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15

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Yoshihiro Matsumoto

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1998-04-01T00:00:00Z

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