Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.
about
Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammalsExpression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint controlThe BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatmentBRCA1 and BRCA2 proteins: roles in health and diseaseBreastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriersBRCA1 inhibition of telomerase activity in cultured cellsThe BRCA2 gene product functionally interacts with p53 and RAD51BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cellsRegulation of BRCA1 expression and its relationship to sporadic breast cancerRole of BRCA gene dysfunction in breast and ovarian cancer predisposition.RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary adenocarcinomasIdentification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors.Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferationThymic model for examining BRCA2 expression and functionThe breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.Chromosome 8p alterations in sporadic and BRCA2 999del5 linked breast cancer.Transcriptional regulation of the base excision repair pathway by BRCA1BRCA1 and prostate cancer.Estrogen receptor coregulators and pioneer factors: the orchestrators of mammary gland cell fate and development.Hunk is required for HER2/neu-induced mammary tumorigenesis.Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomasBrca2 deficiency leads to T cell loss and immune dysfunction.From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer.Oestrogen-mediated phosphorylation and stabilization of BRCA2 protein in breast.In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cellsImplication of BRCA2 -26G>A 5' untranslated region polymorphism in susceptibility to sporadic breast cancer and its modulation by p53 codon 72 Arg>Pro polymorphismDynamic interactions between the promoter and terminator regions of the mammalian BRCA1 geneBRCA1, hormone, and tissue-specific tumor suppressionRisk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study.Molecular biological aspects on canine and human mammary tumors.BRCA1--conductor of the breast stem cell orchestra: the role of BRCA1 in mammary gland development and identification of cell of origin of BRCA1 mutant breast cancer.DNA damage induces p53-dependent BRCA1 nuclear export.Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines.Expression of Brca1 and splice variant Brca1delta11 RNA levels in mouse mammary gland during normal development and tumorigenesis.Characterization of six tumor suppressor genes and microsatellite instability in hepatocellular carcinoma in southern African blacks.Isolation and initial characterization of the BRCA2 promoter.Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice.Mammary gland architecture as a determining factor in the susceptibility of the human breast to cancer.BRCA2-null embryonic survival is prolonged on the BALB/c genetic background.
P2860
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P2860
Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Developmental expression of Br ...... entiation in multiple tissues.
@en
Developmental expression of Br ...... entiation in multiple tissues.
@nl
type
label
Developmental expression of Br ...... entiation in multiple tissues.
@en
Developmental expression of Br ...... entiation in multiple tissues.
@nl
prefLabel
Developmental expression of Br ...... entiation in multiple tissues.
@en
Developmental expression of Br ...... entiation in multiple tissues.
@nl
P2093
P356
P1476
Developmental expression of Br ...... entiation in multiple tissues.
@en
P2093
P304
P356
10.1006/DBIO.1997.8526
P407
P577
1997-04-01T00:00:00Z