N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation. - Wikidata - awgldk - TriplyDB

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

http://www.wikidata.org/entity/Q48136087

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Glycogen synthase kinase 3: more than a namesake Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime Gsk3 Signalling and Redox Status in Bipolar Disorder: Evidence from Lithium Efficacy Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A Effect of Ca2+ on the microtubule-severing enzyme p60-katanin. Insight into the substrate-dependent activation mechanism Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms.Jejunal proteins secreted by db/db mice or insulin-resistant humans impair the insulin signaling and determine insulin resistance Distinct molecular regulation of glycogen synthase kinase-3alpha isozyme controlled by its N-terminal region: functional role in calcium/calpain signaling.Myocardial matrix metalloproteinase-2: inside out and upside down.Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease.Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease.Glycogen accumulation in cardiomyocytes and cardiotoxic effects after 3NPA treatment Glycogen synthase kinase-3 is essential for β-arrestin-2 complex formation and lithium-sensitive behaviors in mice Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders Neuroprotective action of lithium in disorders of the central nervous system.Calpain dysregulation in Alzheimer's disease Site-specific phosphorylation protects glycogen synthase kinase-3β from calpain-mediated truncation of its N and C termini.Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.Regulation of the Arabidopsis GSK3-like kinase BRASSINOSTEROID-INSENSITIVE 2 through proteasome-mediated protein degradation.Mechanistic role of calpains in postischemic neurodegeneration.Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration Glycogen Synthase Kinase 3β Inhibition Improves Myocardial Angiogenesis and Perfusion in a Swine Model of Metabolic Syndrome The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease.Role of Calpain in Pathogenesis of Human Disease Processes.Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling.High glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells.Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism.Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases.Physiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation.Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies.Understanding the relationship between GSK-3 and Alzheimer's disease: a focus on how GSK-3 can modulate synaptic plasticity processes.GSK-3β, a pivotal kinase in Alzheimer disease.Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells.C-terminal truncation of GSK-3β enhances its dephosphorylation by PP2A.Calpain-1 and Calpain-2: The Yin and Yang of Synaptic Plasticity and Neurodegeneration.Mitochondrial Ca2+ and regulation of the permeability transition pore.Atrial Calpains: Mediators of Atrialmyopathies in Atrial Fibrillation.

P2860

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P2860

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

http://www.wikidata.org/entity/Q48136087

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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name

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@en

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@nl

type

label

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@en

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@nl

prefLabel

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@en

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@nl

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Journal of Biological Chemistry

P1476

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

@en

P2093

Félix Hernández

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Jesús Avila

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Paloma Goñi-Oliver

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P2860

A molecular mechanism for the effect of lithium on development

Structure of GSK3beta reveals a primed phosphorylation mechanism

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation

Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter

The calpain system

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

beta-catenin is a target for the ubiquitin-proteasome pathway

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22406-22413

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scholarly article

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10.1074/JBC.M702793200

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31

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282

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2007-06-14T00:00:00Z

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17569662

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