1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost?
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Dopamine transporter mRNA content in human substantia nigra decreases precipitously with ageDifferential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the ratCell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protectionAn endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease.Selective neuronal vulnerability to oxidative stress in the brain.Using 'omics' to define pathogenesis and biomarkers of Parkinson's disease.Dopamine uptake sites in the striatum are distributed differentially in striosome and matrix compartmentsBehavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expressionProteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative diseasePattern of dopaminergic loss in the striatum of humans with MPTP induced parkinsonismMotor cortex stimulation: mild transient benefit in a primate model of Parkinson diseaseAnimal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling PathwaysSusceptibility to a parkinsonian toxin varies during primate developmentApoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice.Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.Mitochondrial mechanisms of neurotoxicity.Cerebral causes and consequences of parkinsonian resting tremor: a tale of two circuits?Direct intranigral injection of dopaminochrome causes degeneration of dopamine neuronsRole of activity-dependent mechanisms in the control of dopaminergic neuron survival.Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.Reversible Pharmacological Induction of Motor Symptoms in MPTP-Treated Mice at the Presymptomatic Stage of Parkinsonism: Potential Use for Early Diagnosis of Parkinson's Disease.1-Methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells is enhanced by preventing glycolysis.Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques.1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A.Potentiation by the tetraphenylboron anion of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its pyridinium metabolite.Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys.Dopamine pathway loss in nucleus accumbens and ventral tegmental area predicts apathetic behavior in MPTP-lesioned monkeys.Preclinical models of Parkinson's disease.Metabolic enzyme expression in dopaminergic neurons in Parkinson's disease: an in situ hybridization study.Novel observations with FDOPA-PET imaging after early nigrostriatal damage.Cerebral metabolic effects of monoamine oxidase inhibition in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine acutely treated monkeys.Heterogeneity of electrically evoked dopamine release and reuptake in substantia nigra, ventral tegmental area, and striatum.Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson's disease.Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons.Melatonin reduces the expression of alpha-synuclein in the dopamine containing neuronal regions of amphetamine-treated postnatal rats.Intracarotid 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration: biochemical and behavioral observations in a primate model of hemiparkinsonism.Pale neurites, premature α-synuclein aggregates with centripetal extension from axon collaterals.Evidence for Sprouting of Dopamine and Serotonin Axons in the Pallidum of Parkinsonian Monkeys.
P2860
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P2860
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost?
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@en
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@nl
type
label
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@en
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@nl
prefLabel
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@en
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@nl
P2093
P1433
P1476
1-Methyl-4-phenyl-1,2,3,6-tetr ...... dopaminergic neurons are lost?
@en
P2093
P304
P356
10.1016/0306-4522(88)90320-X
P407
P577
1988-01-01T00:00:00Z