Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis.
about
Regression to the mean and predictors of MRI disease activity in RRMS placebo cohorts--is there a place for baseline-to-treatment studies in MS?Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data.A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosisClinical trials in progressive multiple sclerosis: lessons learned and future perspectivesSample Size Reassessment and Hypothesis Testing in Adaptive Survival TrialsPharmacological Approaches to the Management of Secondary Progressive Multiple Sclerosis.Some recommendations for multi-arm multi-stage trialsFlexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial.Improving clinical trials for cardiovascular diseases: a position paper from the Cardiovascular Round Table of the European Society of Cardiology.Estimation in multi-arm two-stage trials with treatment selection and time-to-event endpoint.A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints.Software tools for implementing simulation studies in adaptive seamless designs: introducing R package ASD.
P2860
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P2860
Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@en
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@nl
type
label
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@en
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@nl
prefLabel
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@en
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@nl
P2093
P2860
P50
P921
P356
P1476
Designing a seamless phase II/ ...... ication in multiple sclerosis.
@en
P2093
E Valdes Marquez
J Chataway
R Nicholas
P2860
P304
P356
10.1002/SIM.4202
P407
P577
2011-02-22T00:00:00Z