Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95.
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Perspective of synaptic protection after post-infarction treatment with statinsCalpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivoTau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse modelAltered mRNA editing and expression of ionotropic glutamate receptors after kainic acid exposure in cyclooxygenase-2 deficient mice.Inhibition of NR2B phosphorylation restores alterations in NMDA receptor expression and improves functional recovery following traumatic brain injury in miceForebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function.E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity.Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons.Physiological Roles of Calpain 1 Associated to Multiprotein NMDA Receptor ComplexNMDA receptors promote neurogenesis in the neonatal rat subventricular zone following hypoxic‑ischemic injury.NR2A and NR2B subunits differentially mediate MAP kinase signaling and mitochondrial morphology following excitotoxic insult.Calpain-mediated signaling mechanisms in neuronal injury and neurodegenerationStroke patients develop antibodies that react with components of N-methyl-D-aspartate receptor subunit 1 in proportion to lesion sizePretreated quercetin protects gerbil hippocampal CA1 pyramidal neurons from transient cerebral ischemic injury by increasing the expression of antioxidant enzymesHuntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of diseaseNeuroprotection by GDNF in the ischemic brain.Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity.Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicityPro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.NMDA Receptor Expression in the Thalamus of the Stargazer Model of Absence Epilepsy.A control system analysis of the dynamic response of N-methyl-D-aspartate glutamate receptors to alcoholism and alcohol withdrawal.Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury.Functions of the multi-interacting protein KIDINS220/ARMS in cancer and other pathologies.Calpain-2 as a therapeutic target for acute neuronal injury.Effects of fluoride on synaptic membrane fluidity and PSD-95 expression level in rat hippocampus.P38 MAPK inhibition protects against glutamate neurotoxicity and modifies NMDA and AMPA receptor subunit expression.GluN2B N-methyl-D-aspartic acid receptor subunit mediates atorvastatin-Induced neuroprotection after focal cerebral ischemia.Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.Biomarkers for acute diagnosis and management of stroke in neurointensive care units
P2860
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P2860
Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Excitotoxicity and focal cereb ...... he scaffolding protein PSD-95.
@en
Excitotoxicity and focal cereb ...... he scaffolding protein PSD-95.
@nl
type
label
Excitotoxicity and focal cereb ...... he scaffolding protein PSD-95.
@en
Excitotoxicity and focal cereb ...... he scaffolding protein PSD-95.
@nl
prefLabel
Excitotoxicity and focal cereb ...... he scaffolding protein PSD-95.
@en
Excitotoxicity and focal cereb ...... he scaffolding protein PSD-95.
@nl
P2860
P50
P356
P1433
P1476
Excitotoxicity and focal cereb ...... the scaffolding protein PSD-95
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.MP.4002017
P407
P577
2007-05-08T00:00:00Z