about
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like propertiesThe gastrointestinal tumor microenvironmentIKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.Immunity, Inflammation, and CancerActivation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathwayNF-kappaB: linking inflammation and immunity to cancer development and progressionPseudo-HE images derived from CARS/TPEF/SHG multimodal imaging in combination with Raman-spectroscopy as a pathological screening toolMurine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci.IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis.Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia.Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors.TGF alpha transgenic mice. A model of pancreatic cancer development.High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer.Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.Opioid receptors from a lower vertebrate (Catostomus commersoni): sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution.TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases.IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium.Bcl-2 is a critical mediator of intestinal transformationOpposing functions of IKKbeta during acute and chronic intestinal inflammation.ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.Trp53 deficiency protects against acute intestinal inflammation.IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis.IKK- and NF-κB-mediated functions in carcinogenesis.The architect who never sleeps: tumor-induced plasticity.Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators.The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine.High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis.Inflammation and cancer: tissue regeneration gone awry.Selective in vivo imaging of syngeneic, spontaneous, and xenograft tumors using a novel tumor cell-specific hsp70 peptide-based probe.Mesenchymal Cells in Colon Cancer.Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERKCard9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer.IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.Genetically induced pancreatic adenocarcinoma is highly immunogenic and causes spontaneous tumor-specific immune responses.Regulation of cyclin D1 expression by autocrine IGF-I in human BON neuroendocrine tumour cells.Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis.
P50
Q24307391-71F43DC1-D0DB-4122-96FE-1806145FF389Q26827391-9EE40AEF-E271-42F4-8FC6-33AB548DE9DEQ27308754-73B0EB4C-E835-4FC0-9BA3-3E132A0E4FD8Q27861048-EE15A3D7-627B-415E-96E3-4B59BE7574C4Q28214369-B930295D-9B27-4AA7-B6D7-80A2CB5F2877Q29614597-0D259765-87E2-4BA7-B840-3EE9062078C7Q30378079-0B10E9CD-42E0-4611-8FAB-F44CC78C9EF8Q30744989-E11F544E-3E39-45B3-8654-C9E1CE99E7F2Q33561833-A5A2BC1D-1D77-402B-8FB0-C095C2AE5B06Q33899678-E54BD703-856E-4C9A-B2CF-000205A52BF0Q33959754-1EA3E6AD-6FDE-4B7F-9763-AF16781904C6Q34139143-0DECBBB9-C665-4088-8A53-E33E993F0C25Q34518703-2D157DDF-E756-4D7F-A8BB-EC14F2A9DB00Q34835806-B7E82AB8-00AB-4544-8A89-C28C6A82CA4FQ35687935-5B21A146-D6A0-4E67-AC81-188835FF4447Q35741686-BB94A9C8-E532-4D31-8225-AD6CE4B99340Q36259805-1085E217-405F-45B5-9DAF-F933DED88299Q36304802-16B10824-B78E-44D4-95BB-EC131AD8E0D4Q36557145-18696037-E4A8-49C0-8E01-04457F51114DQ36602345-AF64025F-529B-4088-8D68-CB879D3DCB9AQ36675203-ED2783F6-FE83-4F5A-B014-B24365A5BFF0Q36937167-D762B1C2-4CCF-4E60-8C9A-407758940CF0Q36949354-56BADBCB-DDA9-4B75-AA2C-6C3709D44643Q37008316-1C466CDA-5007-48EF-8522-8B5BEB2C4E8AQ37679965-714DBA68-F1A0-4E87-BE48-F695967F8B31Q37789195-98912643-6D15-4E6F-86A0-286D9F6D6C9EQ38220439-30B72A2F-8632-47B2-8517-5DE7FFED5328Q38320912-648301E3-883D-4531-A067-807465E26686Q38785994-8ADEC4E9-BB10-4765-BA54-202E84C3A1E3Q38886747-8454BDD6-D550-4093-87A1-7AD5FD75724DQ38926934-DD925F62-2D09-46C2-B9DA-56B1959C73DFQ38949312-D71D85EF-348D-4D55-A0CF-5334EA5734FCQ39098140-56E35823-8E92-418D-8753-6845B6CC7865Q39109989-F771F238-9D37-4F67-8B66-C555BF227A25Q39172441-24A7F6A8-0DF4-493E-B43B-6BEE6CEFDA85Q40183418-A12BD486-A2DF-41BA-A57B-56694D4C7055Q40244730-CF96E112-4BB4-4CBB-BF17-94964899C27EQ40333018-4DB29DF5-6C10-4138-BA07-3DFEEF657FA9Q40484671-C27B63C7-ADF8-4DFC-BE9A-3EDEE5DB263AQ40687138-5900AD2D-8175-440D-B1B7-54B63E30FBC2
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Florian R Greten
@ast
Florian R Greten
@en
Florian R Greten
@es
Florian R Greten
@nl
Florian R Greten
@sl
type
label
Florian R Greten
@ast
Florian R Greten
@en
Florian R Greten
@es
Florian R Greten
@nl
Florian R Greten
@sl
prefLabel
Florian R Greten
@ast
Florian R Greten
@en
Florian R Greten
@es
Florian R Greten
@nl
Florian R Greten
@sl
P106
P21
P31
P496
0000-0002-3928-6080