NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. - Wikidata - awgldk - TriplyDB

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

http://www.wikidata.org/entity/Q36259805

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Cell death programs in Yersinia immunity and pathogenesis The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency Emerging roles for the non-canonical IKKs in cancer Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls The inflammasome: in memory of Dr. Jurg Tschopp Resolution of Inflammation: What Controls Its Onset?Innate Immune Response in Brain, NF-Kappa B Signaling and Cystatins The two faces of receptor interacting protein kinase-1 IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.The NF-κB subunit RelA/p65 is dispensable for successful liver regeneration after partial hepatectomy in mice Immunity, Inflammation, and Cancer Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner.Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer A multi-targeted approach to suppress tumor-promoting inflammation Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis Tumor suppressor p53 functions as a negative regulator in IgE-mediated mast cell activation Inflammasome-mediated IL-1β production in humans with cystic fibrosis Carcinoembryonic antigen-related cell adhesion molecule-1 regulates granulopoiesis by inhibition of granulocyte colony-stimulating factor receptor IKK2 inhibition attenuates laser-induced choroidal neovascularization IKK2 inhibition using TPCA-1-loaded PLGA microparticles attenuates laser-induced choroidal neovascularization and macrophage recruitment A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide Inflammation meets cancer, with NF-κB as the matchmaker An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production.An additional piece in the puzzle of neutrophil-derived IL-1β: the NLRP3 inflammasome.Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.IL-1beta processing in host defense: beyond the inflammasomes.IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.IKK/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis.Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome.Induction and termination of inflammatory signaling in group B streptococcal sepsis.Maintenance of IKKβ activity is necessary to protect lung grafts from acute injury Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes.Chronic cyclooxygenase-2 inhibition promotes myofibroblast-associated intestinal fibrosis.Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites.Top Notch cancer stem cells by paracrine NF-κB signaling in breast cancer.

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P2860

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

http://www.wikidata.org/entity/Q36259805

description

2007 nî lūn-bûn

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2007年の論文

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2007年學術文章

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2007年學術文章

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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J.CELL.2007.07.009

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NF-kappaB is a negative regula ...... logical inhibition of IKKbeta.

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Bruce B Jaffee

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Cornelius Miething

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Dirk H Busch

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Jason Goode

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Joshua Fierer

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Julia Bollrath

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Justus Duyster

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Lars Eckmann

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Melek C Arkan

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Michael Neuenhahn

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P2860

ICEBERG: a novel inhibitor of interleukin-1beta generation

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

Interleukin 1 is processed and released during apoptosis

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

Neutrophil serine proteases: specific regulators of inflammation

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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17803913

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